Abstract
Variable number of tandem repeats (VNTR) loci are highly informative markers for linkage analysis and identity testing. In addition to the variation in the number of repeats, some VNTR loci display variabilty of the repeat sequence so that an additional polymorphism level can be observed analyzing the interspersion pattern of variant repeats along the tandem repeat array (Jeffreys et al. 1991; Neil and Jeffreys 1993). For the majority of VNTR loci, however, the extent of polymorphism of the flanking sequences is not known, despite some early studies showing linkage between VNTR specific-alleles and nearby RFLPs (Higgs et al. 1986; Cox et al. 1988; Renges et al. 1992; Martinson et al. 1994).
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© 1996 Springer-Verlag Berlin Heidelberg
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Albarrán, C. et al. (1996). Analysis of D1S80 VNTR Allele Polymorphism and Association with a Nearby Flanking Sequence Polymorphism in Two Spanish Populations. In: Carracedo, A., Brinkmann, B., Bär, W. (eds) 16th Congress of the International Society for Forensic Haemogenetics (Internationale Gesellschaft für forensische Hämogenetik e.V.), Santiago de Compostela, 12–16 September 1995. Advances in Forensic Haemogenetics, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80029-0_39
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DOI: https://doi.org/10.1007/978-3-642-80029-0_39
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