Abstract
For extracting the full information about stains or an identification situation, it is advisable to investigate karyotic STR systems as well as mitochondria (mt) DNA. Each of the above strategies is associated with special advantages and disadvantages:
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1.
Due to the high number of mt copies per cell, it is a much higher sensitivity what distinguishes mt testing from other methods.
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2.
Since mt concerns maternally inherited markers, it avoids wrong results due to illegitamate paternities.
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3.
mt testing can be superior if mixed stains have to be investigated. Stain sorting by cloning is possible.
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References
Piercy R, Sullivan KM, Benson N, Gill P (1993) The application of mitochondrial DNA typing to the study of white Caucasian geneticc identification. Int J Med 106: 85–90
Sullivan KM, Hopgood R, Gill P (1991) Automated amplification and sequencing of human mitochondrial DNA. Electrophoresis 12: 17–21
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© 1996 Springer-Verlag Berlin Heidelberg
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Szibor, R., Plate, I., Kirches, E., Krause, D. (1996). Mixing and Thermic Treatment of Mitochondrial PCR Fragments Reveal Sequence Differences by Heteroduplex Formation -A Rapid Method for Forensic Identity Testing. In: Carracedo, A., Brinkmann, B., Bär, W. (eds) 16th Congress of the International Society for Forensic Haemogenetics (Internationale Gesellschaft für forensische Hämogenetik e.V.), Santiago de Compostela, 12–16 September 1995. Advances in Forensic Haemogenetics, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80029-0_3
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DOI: https://doi.org/10.1007/978-3-642-80029-0_3
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