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Part of the book series: Advances in Forensic Haemogenetics ((HAEMOGENETICS,volume 6))

Abstract

Short Tandem Repeat (STR) profiling is rapidly growing as a method of individual identification for forensic and other purposes. Several multiplex STR systems are available (e.g. Kimpton et al, 1993), offering matching probabilities of about 10-4. The quadruplex STR system developed in our laboratory and presently in use in forensic casework gives a matching probability of this order in three British populations (Kimpton et al, 1993). We have investigated numerous STR loci for use in further multiplex STR systems. Here we discuss the criteria for locus selection, with particular reference to the repeat sequence at the loci under investigation.

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References

  • Adams M, Urquhart A, Kimpton C, Gill P (1993) The human D11S554 locus: four distinct families of repeat pattern alleles at one locus. Hum. Molec. Genet. 2: 1373–1376

    Article  PubMed  CAS  Google Scholar 

  • Barber M, McKeown B, Parkin B (to be published) Structural variation in the alleles of a short tandem repeat system at the human alpha fibrinogen locus (HumFGA). Forensic Sci. Int.

    Google Scholar 

  • Gill P, Urquhart A, Millican E, Oldroyd N, Watson S, Kimpton C (to be published) Criminal intelligence databases and interpretation of STRs. Adv. Forensic Haemogenetics

    Google Scholar 

  • Kimpton CP, Gill P, Walton A, Urquhart A, Millican ES, Adams M (1993) Automated DNA profiling employing multiplex amplification of short tandem repeat loci. PCR Methods Applications 3: 13–22

    CAS  Google Scholar 

  • Puers C, Hammond HA, Jin L, Caskey CT, Schumm JW (1993) Identification of repeat sequece homogeneity at the polymorphic short tandem repeat locus HUMTHO1[AATG]n and reassignment of alleles in population analysis by using a locis-specific allelic ladder. Am. J. Hum. Genet. 53: 953–958

    PubMed  CAS  Google Scholar 

  • Robertson JM, Badger CA, Buoncristiani MR (1995) Design of short tandem repeat systems suitable for human identification. Proc. 5th Intl. Symposium on Human Identification 1994. Promega Corp.

    Google Scholar 

  • Urquhart A, Kimpton CP, Doownes TJ, Gill P (1994) Variation in short tandem repeat sequences: a survey of twelve microsatellite loci for use as forensic identification markers. Int. J. Leg. Med. 107: 13–20

    Article  CAS  Google Scholar 

  • Urquhart A, Kimpton CP, Gill P (1993) Sequence variability of the tetranucleotide repeat of the human beta-actin related pseudogene H-beta-Ac-psi-2 (ACTBP2) locus. Hum. Genet. 92: 637–638

    Article  PubMed  CAS  Google Scholar 

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© 1996 Springer-Verlag Berlin Heidelberg

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Urquhart, A.J. et al. (1996). Selection of STR loci for forensic identification systems. In: Carracedo, A., Brinkmann, B., Bär, W. (eds) 16th Congress of the International Society for Forensic Haemogenetics (Internationale Gesellschaft für forensische Hämogenetik e.V.), Santiago de Compostela, 12–16 September 1995. Advances in Forensic Haemogenetics, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80029-0_28

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  • DOI: https://doi.org/10.1007/978-3-642-80029-0_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-60492-1

  • Online ISBN: 978-3-642-80029-0

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