DNA PCR Polymorphisms in Paternity Test Protocols. A Biostatistical Approach
Over the years there has been a continuous increase of the number of genetic polymorphisms which have become available for paternity testing. The range has extended from the red blood cell groups, through serum proteins and erythrocyte enzymes polymorphisms to white cells antigens of the HLA system. With these “classical” markers, the use of several laboratory techniques is needed to achieve a sufficiently high standard of efficiency both in paternity exclusion and inclusion.
KeywordsInclusion Probability Paternity Testing Paternity Relationship Paternity Exclusion Gene Geography
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- Bargagna M, Domenici R (1988) L’esclusione di paternità. In: Bargagna M, Domenici R, Giari A (eds) Applicazioni medico-legali delia immunoematologia. Masson, Milano pp 89–103Google Scholar
- Domenici R, Fornaciari S, Nardone M, Ricciardi MF, Spinetti I, Venturi M, Bargagna M (1994a) Study of the Apo B Polymorphism in Tuscany (Italy). Adv Forens Haemogenet 5:493–495Google Scholar
- Domenici R, Nardone M, Spinetti I, Venturi M, Bargagna M, Cucurachi N, Buscemi L, Regazzi E, Ferrara D, Previderè C, Peloso G, Tagliabracci A, Mencarelli R (1994b) The distribution of HumTH01 Polymorphism in Northern and Central Italy. Adv Forens Haemogenet 5:496–498Google Scholar
- Garber RA, Morris JW (1983) General equations for the average power of exclusion for genetic systems of n codominant alleles in one-parent and no-parent cases of disputed parentage. In: Walker RH (ed) Inclusion probabilities in parentage testing. AABB, Arlington, VA, pp 277–280Google Scholar
- Mayr WR, Rossi U, eds (1993) Basic methods and criteria for paternity investigations. Proceedings Educational Course following 15th Int Congr Int Soc Forens HaemogenetGoogle Scholar
- Morris JW (1983) Relationships between power of exclusion and probability of paternity. In: Walker RH (ed) Inclusion probabilities in parentage testing. AABB, Arlington, VA, pp 267–275Google Scholar
- Nijenhuis LE (1979) Some mathematical aspects of the paternity index (I=X/Y) and their application in a statistical material. Proceedings 8th Int Congr Soc Forens Haemogenet pp 584–589Google Scholar
- Tagliabracci A, Paoli M, Rodriguez D, Buscemi L, Cucurachi N, Ferrara SD, Previderè C, Peloso G, Riva A, Pierucci G, Domenici R, Fornaciari S, Spinetti I, Nardone M, Bargagna M. (1995) Allele frequencies of the HUMFES/FPS system in Northern and Central Italy. Abstracts 16th Int Congr Int Soc Forens HaemogenetGoogle Scholar