Allele Frequencies of the HUMFES/FPS System in Northern and Central Italy
The tetrameric (ATTT) short tandem repeat HUMFES/FPS system, located on chromosome 15 (15q25-qter), displays a polymorphism (Polymeropoulos et al. 1991) which has been investigated for forensic purposes (Hammond et al. 1994). The aim of the present work was to study the polymorphism of this system in a large Italian population sample: 1) to verify allele frequency distribution, 2) to check whether allele frequencies show inter-regional differences, 3) to evaluate the effectiveness of this system for paternity testing and personal identification. For this purpose, collaborative research was performed on subjects from four Italian regions in laboratories of the Institutes of Legal Medicine of the Universities of Pavia (Lombardy), Parma (Emilia), Pisa (Tuscany) and Ancona (Marches).
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