Analysis of the Short Tandem Repeat Polymorphism D18S51: Allele Frequencies and Sequence Studies
The analysis of Short Tandem Repeat polymorphisms is widely used as a method for human identification. There is a demand to combine several STR loci with high discrimination power for multiplex analysis. STR polymorphisms with few alleles (e.g.: TC11, F13A) do not have the discrimination power compared to STR-systems like SE33 (ACTBP2). SE33 has more than 30 alleles and thus the space for the combination with other STR loci in multiplex analysis is reduced. Therefore STR polymorphisms like FGA (HUMFIBRA) and D18S51 with about 15–20 alleles seem to be a good compromise.
KeywordsDMSO Electrophoresis Nylon dNTP Formamide
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