Analysis of the Short Tandem Repeat Polymorphism D18S51: Allele Frequencies and Sequence Studies
The analysis of Short Tandem Repeat polymorphisms is widely used as a method for human identification. There is a demand to combine several STR loci with high discrimination power for multiplex analysis. STR polymorphisms with few alleles (e.g.: TC11, F13A) do not have the discrimination power compared to STR-systems like SE33 (ACTBP2). SE33 has more than 30 alleles and thus the space for the combination with other STR loci in multiplex analysis is reduced. Therefore STR polymorphisms like FGA (HUMFIBRA) and D18S51 with about 15–20 alleles seem to be a good compromise.
KeywordsShort Tandem Repeat Short Tandem Repeat Locus Multiplex Analysis Allele Length GAAA Repeat
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- Berschick P, Henke J, Henke L (1995) Analysis of the Short Tandem Repeat polymorphism SE33: A new high resolution separation of SE33 by means of direct blotting electrophoresis. In: Bär W, Fiori A, Rossi U (eds) Advances in Forensic Haemogenetics 5, Springer, Berlion Heidelberg, New York, p 323–325Google Scholar