Abstract
Radioimmunotherapy using 131I-labeled antibodies has been shown to be very efficient in patients with B cell lymphoma: 85% of patients responded with complete remission upon myeloablative therapy using radiolabeled MB-1 and B1 antibody (Press et al. 1993). In treatment of solid tumors, however, such response rates have not been reached (Mach et al. 1991; Goldenberg and Schlom 1993; Breitz et al. 1992).
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Buchegger, F., Mach, JP., Folli, S., Delaloye, B., Bischof-Delaloye, A., Pèlegrin, A. (1996). Higher Efficiency of 131I-Labeled Anti-Carcinoembryonic Antigen—Monoclonal Antibody F(ab′)2 as Compared to Intact Antibodies in Radioimmunotherapy of Established Human Colon Carcinoma Grafted in Nude Mice. In: Sautter-Bihl, ML., Bihl, H., Wannenmacher, M. (eds) Systemic Radiotherapy with Monoclonal Antibodies. Recent Results in Cancer Research, vol 141. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79952-5_3
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