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Influence of Nitric Oxide on Cardiac Systolic and Diastolic Function

  • Chapter
Role of Nitric Oxide in Sepsis and ADRS

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 24))

  • 55 Accesses

Abstract

The highly reactive gas, nitric oxide (NO), is now recognized to be a ubiquitous inter- and intra-cellular signaling molecule which has pivotal roles in many physiological processes, e.g. endothelial regulation of vascular smooth muscle tone and smooth muscle cell proliferation, inhibition of platelet adhesion and aggregation, peripheral and central neurotransmission, macrophage cytotoxicity, etc. (for reviews, see [1, 2]). In addition, an increasing body of data implicates abnormalities of NO pathway in several pathophysiological processes. The present chapter focuses on recent work which indicates that NO also has important physiological and pathophysiological influences on myocardial contractile function.

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Authors
  1. A. M. Shah
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Editors and Affiliations

  1. Department of Surgery, Beth Israel Hospital, 330 Brookline Avenue, 02215, Boston, MA, USA

    M. P. Fink

  2. Department of Anesthesiology and Intensive Care, Lariboisière University Hospital, 2 rue Ambroise Paré, 75475, Paris Cedex 10, France

    Didier Payen

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© 1995 Springer-Verlag Berlin Heidelberg

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Shah, A.M. (1995). Influence of Nitric Oxide on Cardiac Systolic and Diastolic Function. In: Fink, M.P., Payen, D. (eds) Role of Nitric Oxide in Sepsis and ADRS. Update in Intensive Care and Emergency Medicine, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79920-4_7

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  • DOI: https://doi.org/10.1007/978-3-642-79920-4_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79922-8

  • Online ISBN: 978-3-642-79920-4

  • eBook Packages: Springer Book Archive

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