Abstract
There is now an increasing body of evidence which strongly suggests that excess production of nitric oxide (NO) is responsible for the severe hypotension commonly seen in septic shock. Very recently, Gomez-Jimenez et al. [1] have shown that plasma nitrite and nitrate levels were not different between a control group of patients and those with sepsis, but the values in both these groups were significantly lower than in a group of patients with septic shock. In addition, they were able to show a correlation between nitrite and nitrate levels and cardiac output and plasma endotoxin levels in the septic group.
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© 1995 Springer-Verlag Berlin Heidelberg
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Bennett, E.D. (1995). Inhibition of Nitric Oxide Production in Clinical Septic Shock. In: Fink, M.P., Payen, D. (eds) Role of Nitric Oxide in Sepsis and ADRS. Update in Intensive Care and Emergency Medicine, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79920-4_17
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DOI: https://doi.org/10.1007/978-3-642-79920-4_17
Publisher Name: Springer, Berlin, Heidelberg
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