Zusammenfassung
Bislang liegen erst wenige Untersuchungen zu suizidalen und aggressiven Verhalttensweisen bei Patienten mit funktionellen Psychosen mit Hilfe bildgebender Verfahren — insbesondere SPECT und PET – vor. In einer von den Autoren durchgefuhrten Untersuchung an 113 Patienten mit und ohne manifeste selbst- oder fremdaggressive Verhaltensweiden, Bei Patienten mit Persölichkeitsstörungen und anderen psychiatrischen Erkrankungen und aggressiven Verhalttensweisen zeigte sich jedoch, daβ eine verminderte Glukoseutilisation und eine reduzierte Hirndurchblutung im Bereich des frontoorbitalen Cortex überdurchschnittlich stark mit gehäuften oder besonders schwerweigenden aggressiven Verhalten in der Anamnese korrelierte. Von erhebblichem Interesse ist die Bezziehung zwischen Befunden bildgebender Untersuchungsverfahren und histopathologischen Methoden bei Patienten unterschiedlicher diagnostischer Zuordnung mit aggressiven und autoaggressiven Verhaltensweisen.
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Literatur
Altshuler LL, Casanova MF, Goldberg TE, Kleinman JE (1990) The hippocampus and parahippo- campus in schizophrenic, suicide, and control brains. Arch Gen Psychiatry 47: 1029–1034
American Psychiatric Association. DSM-III-R (1987) Diagnostic and statistical manual of mental disorders 3rd ed, revised. American Psychiatric Press, Washington DC
Anisman H, Irwin J, Sklar LS (1979a) Deficits of escape performance following catecholamine depletion: Implications for behavioral deficits induced by uncontrollable stress. Psychopharmacology 64: 163–170
Anisman H, Remington G, Sklar LS (1979b) Effect of inescapable shock on subsequent escape performance: Catecholamine and cholinergic mediation of response initiation and maintenance. Psychopharmacology 61: 107–124
Baron JC, Samson Y, Comar D, Crouzel C, Deniker P, Agid Y (1985) Étude in vivo des récepteurs sérotoninergiques centraux chez l’homme par tomographic a positions. Rev Neurol (Paris) 141: 537–545
Bouhuys A, Flentge F, Hoofdakker RH van den (1991) Effects of total sleep deprivation on urinary Cortisol, self-rated arousal, and mood in depressed patients. Psychiatry Res 34: 149–162
Burg W van den, Hoofdakker RH van den (1975) Total sleep deprivation in endogenous depression. Arch Gen Psychiatry 32: 1121–1125
Creese I (1985) Dopamine and antipsychotic medications. In: Hales RE, Frances AJ (eds) Annual review of psychiatry, No. 4. APA Press, Washington DC, pp 17–36
Cummings JL (1985) Psychosomatic aspects of movement disorders. Adv Psychosom Med 13: 111 - 132
Ebert D, Feistel H, Barocka A (1991) Effects of sleep deprivation on the limbic system and the frontal lobes in affective disorders. Psychiatry Res Neuroimaging 40: 247–251
Ebert D, Kaschka W, Stegbauer P, Schrell U (1993) Prolactin response to sulpiride before and after sleep deprivation in depression. Biol Psychiatry 33: 666–669
Ebert D, Feistel H, Barocka A, Kaschka W (1994a) Increased limbic blood flow and total sleep deprivation in major depression with melancholia. Psychiatry Res Neuroimaging 55: 101–109
Ebert D, Feistel H, Kaschka W, Barocka A, Pirner A (1994b) Single photon emission computerized tomography assessment of cerebral dopamine D2 receptor blockade in depression before and after sleep deprivation - preliminary results. Biol Psychiatry 35: 880–885
Gillin JC, Sitaram N, Wehr T et al. (1984) Sleep and affective illness. In: Post RM, Ballenger JC (eds) Neurobiology of mood disorders. Williams & Wilkins Baltimore, MD
Goyer PF, Andreason PJ, Semple WE et al. (1994) Positron-emission tomography and personality disorders. Neuropsychopharmacology 10: 21–28
Kapur S, Mann JJ (1992) Role of the dopaminergic system in depression. Biol Psychiatry 32: 1–17
Kaschka WP, Ebert D, Feistel H, Barocka A (1994) The dopamine hypothesis of sleep deprivation. Eur Psychiatry 9: 174s
Kasper S, Sack DA, Wehr TA, Kick H, Voll G, Viera A (1988) Nocturnal TSH and prolactin secretion during sleep deprivation and prediction of antidepressant response in patients with major depression. Biol Psychiatry 24: 631–641
Kung HF, Pan S, Kung MP (1989) In vitro and in vivo evaluation of J 123 IBZM. J Nucl Med 30: 88–92
Linkowski P, Cauter E van, L’Hermite-Baleriaux M (1989) The 24-hour profile of plasma prolactin in men with major endogenous depressive illness. Arch Gen Psychiatry 46: 813–819
Logan J, Dewey S, Wolf A (1991) Effects of endogenous dopamine on measures of 18FN- Methylspiroperidol binding in the basal ganglia. Synapse 9: 195–207
Matrin JH (1989) Neuroanatomy. Text and atlas. Elsevier, New York Amsterdam London
Mayeux R (1990) Parkinson’s disease. J Clin Psychiatry 51:7 (Suppl) 20–23
McKinney WT, Kane FJ (1967) Depression with the use of alphamethyldopa. Am J Psychiatry 124: 118–119
Moore KE (1987) Hypothalamic dopaminergic neuronal systems. In: Meitzer HY (ed) Psychopharmacology: The third generation of progress. Raven Press, New York, pp 127–140
Muscat R, Papp M, Willner P (1992) Antidepressant-like effects of dopamine agonists in an animal model of depression. Biol Psychiatry 31: 937–946
Raine A, Buchsbaum MS, Stanley J, Lottenberg S, Abel L, Stoddard J (1994) Selective reductions in prefrontal glucose metabolism in murderers. Biol Psychiatry 36: 365–373
Randrup A, Munkvad I, Fog R et al (1975) Mania, depression, and brain dopamine In: Essman WB, Valzelli L (eds) Current developments in psychopharmacology. Spectrum Publications, New York, pp 207–229
Roth RH, Wolf ME, Deutch AY (1987) Neurochemistry of midbrain dopamine systems. In: Meitzer HY (ed), Psychopharmacology: The third generation of progress. Raven Press, New York, pp 81–94
Roy A, Karoum F, Pollack S (1992) Marked reduction in indexes of dopamine metabolism among patients with depression who attempt suicide. Arch Gen Psychiatry 49: 447–450
Salzman C, Jimerson D, Vasile R, Watsky E, Gerber J (1993) Response to SSRI antidepressants correlates with reduction in plasma HVA: Pilot study. Biol Psychiatry 34: 569–571
Sedvall G (1994) Bildgebende Verfahren in der Psychiatrie - Ausblick. Fortschr Neurol Psychiatr 62: 39–43
Sedvall G, Farde L, Persson A, Wiesel FA (1986) Imaging of neurotransmitter receptors in the living human brain. Arch Gen Psychiatry 43: 995–1005
Seeman P, Niznik HB (1990) Dopamine receptors and transporters in Parkinson’s disease and schizophrenia. FASEBJ 4 (10): 2737–2744
Verhoeff NPLG, Buell U, Costa DC (1992) Basics and recommendations for brain SPECT. Nucl Med 31: 114–131
Willner P (1983a) Dopamine and depression: A review of recent evidence, ii Theoretical approaches. Brain Res Rev 6: 225–236
Willner P (1983b) Dopamine and depression: A review of recent evidence, iii The effects of antidepressant treatments. Brain Res Rev 6: 237–246
Willner P (1991) Animal models as simulations of depression. TiPS 12: 131–136
Wu JC, Gillin, JC, Buchsbaum MS, Hershey T, Johnson JC, Bunney WE (1992) Effect of sleep deprivation on brain metabolism of depressed patients. Am J Psychiatry 149: 538–543
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Kaschka, W.P., Ebert, D., Feistel, H. (1996). Stellenwert bildgebender und neuroendokrinologischer Verfahren bei der Untersuchung funktioneller Psychosen mit aggressivem und suizidalem Verhalten. In: Wolfersdorf, M., Kaschka, W.P. (eds) Suizidalität. Tropon-Symposium, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79855-9_5
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