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Transposable Elements pp 27–48Cite as

Transposon Tn7

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 204))

Abstract

Most transposable elements move at low frequencies and insert into many different target sites, displaying only modest or little target site-selectivity. The bacterial transposon Tn7 (Barth et al. 1976) is distinguished by its ability to insert at high frequency into a specific site called an “attachment” site, or attTn7, in the chromosomes of many bacteria, including Escherichia coli (reviewed by Craig 1989, 1991). In the absence of attTn7, for example when Tn7 inserts into plasmids, Tn7 resembles other elements and transposes to many sites at low frequency. Through both genetic and biochemical studies, it is now known that Tn7 can recognize and transpose to two different types of target sites through the action of two distinct but overlapping sets of Tn7-encoded transposition proteins.

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Author information

Authors and Affiliations

  1. Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, 725 North Wolfe Street, 615 PCTB, 21205, Baltimore, MD, USA

    N. L. Craig

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  1. N. L. Craig
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Editors and Affiliations

  1. Max-Planck-Institut für Züchtungsforschung, Carl-von-Linné-Weg 10, D-50829, Köln, Germany

    Heinz Saedler

  2. Lehrstuhl und Institut für Genetik, Technische Universität München, Lichtenbergstraße 4, D-85747, Garching, Germany

    Alfons Gierl

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© 1996 Springer-Verlag Berlin Heidelberg

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Craig, N.L. (1996). Transposon Tn7. In: Saedler, H., Gierl, A. (eds) Transposable Elements. Current Topics in Microbiology and Immunology, vol 204. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79795-8_2

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  • DOI: https://doi.org/10.1007/978-3-642-79795-8_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79797-2

  • Online ISBN: 978-3-642-79795-8

  • eBook Packages: Springer Book Archive

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