Zusammenfassung
Das klinische Bild der zystischen Fibrose (CF) zeigt sich einmal im gastrointestinalen Bereich, betroffen hiervon sind besonders die Funktionen des Pankreas. Durch die Summe der gastrointestinalen Veränderungen kommt es zu Malabsorption und Maldigestion mit besonderen Störungen der Fettverdauung und somit zur Unterernährung bzw. partiellen Mangelversorgung. Zum anderen kommt es im Bereich der Lunge zu pulmonalen Veränderungen. Die Mortalität und Morbidität bei Patienten mit zystischer Fibrose ist abhängig von der chronisch fortschreitenden pulmonaren Erkrankung (Wood et al. 1976).
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Bartens, C., Götz, M., Elmadfa, I. (1995). Einfluß von chronischer Entzündung auf Parameter des antioxidativen Schutzsystems am Beispiel von Patienten mit zystischer Fibrose. In: Böhles, H. (eds) Oxidativer Stress in der Kinderheilkunde. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79748-4_11
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