Abstract
The retinoids consist of a family of compounds structurally and functionally related to all-trans-retinoic acid, the physiologically active metabolite of vitamin A. While the biology of this class of agents has long been of interest to developmental biologists and to those interested in the physiology of vision, it is much more recently that investigators concerned with the prevention and treatment of malignancy have focussed on this class of agents. This recent attention has been fuelled by the rapid increases in our understanding of the normal biology of the retinoids, the appreciation of their powerful influences on gene expression, and the demonstration of their ability in some preclinical settings to interfere with the malignant process.
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© 1995 Springer-Verlag Berlin Heidelberg
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Degos, L., Parkinson, D.R. (1995). Introduction. In: Degos, L., Parkinson, D.R. (eds) Retinoids in Oncology. ESO Monographs. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79706-4_1
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DOI: https://doi.org/10.1007/978-3-642-79706-4_1
Publisher Name: Springer, Berlin, Heidelberg
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