Skip to main content
SpringerLink
Log in

Besonderheiten der Plasminogenaktivierung von Neugeborenen mit und ohne oxidative Inaktivierung von α 2-Antiplasmin

  • Conference paper
Book cover 25. Hämophilie-Symposion Hamburg 1994

  • 22 Accesses

Zusammenfassung

Die Plasminogenkonzentration und die funktionelle Aktivität sind bei Neugeborenen im Vergleich zu Erwachsenen um ca. 50% vermindert [1–5].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Ambrus CM, Ambrus JL, Choi TS, Jung O, Mirand EA, Bartfay-Szabo A (1979) The fibrino-lysin system and its relationship to disease in the newborn. Am J Pediatr Hematol Oncol 1:251–260

    Article  PubMed  CAS  Google Scholar 

  2. Andrew M, Paes B, Milner R, Johnston M, Mitchell L, Tollefsen DM, Powers P (1987) Development of the human coagulation system in the full term infant. Blood 70:165–172

    PubMed  CAS  Google Scholar 

  3. Corrigan JJ (1988) Neonatal thrombosis and the thrombolytic system: Pathophysiology and therapy. Am J Pediatr Hematol Oncol 10:83–91

    Article  PubMed  Google Scholar 

  4. Corrigan JJ, Sleeth JJ, Jeter MA, Lox CD (1989) Newborn’s fibrinolytic mechanism: Components and plasmin generation. Am J Hematol 32:273–278

    Article  PubMed  CAS  Google Scholar 

  5. Ekelund H, Hedner U, Nilsson IM (1970) Fibrinolysis in newborns. Acta Paediatr Scand 59:33–43

    Article  PubMed  CAS  Google Scholar 

  6. Estelles A, Aznar J, Gilabert J, Parrilla JJ (1980) Dysfunctional plasminogen in full-term newborn. Pediatr Res 14:1180–1185

    Article  PubMed  CAS  Google Scholar 

  7. Benavent A, Estellés A, Aznar J, Martinez-Sales V, Gilabert J, Fornas E (1984) Dysfunctional plasminogen in full term newborn — study of active site of plasmin. Thromb Haemostas 51:67–70

    CAS  Google Scholar 

  8. Al Hilali MM, Gilliver BE (1984) Physiological activation of plasminogen in full term newborn infants. J Clin Pathol 37:1264–1267

    Article  PubMed  CAS  Google Scholar 

  9. Andrew M, Paes, B, Johnston M (1990) Development of the hemostatic system in the neonate and young infant. Am J Pediatr Hematol Oncol 12:95–104

    Article  PubMed  CAS  Google Scholar 

  10. Andrew M, Paes, B, Milner R, Johnston M, Mitchell L, Tollefsen DM, Castle V, Powers P (1988) Development of the human coagulation system in the healthy premature infant. Blood 72:1651–1657

    PubMed  CAS  Google Scholar 

  11. Barnard DR, Simmons MA, Hathaway WE (1979). Coagulation studies in extremely premature infants. Pediatr Res 13:1330–1335

    Article  PubMed  CAS  Google Scholar 

  12. Forestier F, Daffos F, Galactéros F, Bardakijan J, Rainaut M, Benzard Y (1986) Hematological values of 163 normal fetuses between 18 and 30 weeks of gestation. Pediatr Res 20:342–346

    Article  PubMed  CAS  Google Scholar 

  13. Holmberg L, Henriksson P, Ekelund H, Astedt B (1974) Coagulation in the human fetus, comparison with term newborn infants. J Pediatr 85:860–864

    Article  PubMed  CAS  Google Scholar 

  14. Jensen AH, Josso F, Zamet P, Monset-Couchard M, Minkowski A (1973) Evolution of blood clotting factor levels in premature infants during the first 10 days of life: A study of 96 cases with comparison between clinical status and blood clotting factor levels. Pediatr Res 7:638–644

    Article  PubMed  CAS  Google Scholar 

  15. Künzer W (1961) Fetales fibrinogen. Klin Wochenschr 39:536–542

    Article  Google Scholar 

  16. Witt I, Müller H, Künzer W (1969) Evidence for the existence of foetal fibrinogen. Thromb Diath Haemorrh 22:101–109

    PubMed  CAS  Google Scholar 

  17. Schettini F, de Mattia D, Mautone A (1972) Preprothrombin and prothrombin in full term newborns. Haemostasis 1:271–278

    PubMed  CAS  Google Scholar 

  18. Saleh AA, Hirokawa S, Stowers MA, Eldridge DM, Dorey LG, Dombrowski MP, Bottoms SF, Kazzi GM, Mammen EF (1993) Effect of mode of delivery on certain parameters of neonatal hemostasis. Thromb Haemostas 69:1020

    Google Scholar 

  19. Suarez CR, Walenga J, Mangogna LC, Fareed J (1985) Neonatal and maternal fibrinolysis: Activation at time of birth. Am J Hematol 19:365–372

    Article  PubMed  CAS  Google Scholar 

  20. Ekelund H (1972) Fibrinolysis in the first year of life. Acta Paediatr Scand 61:5–10

    Article  PubMed  CAS  Google Scholar 

  21. Thorsen S, Philips M, Selmer J, Lecander I, Astedt B (1988) Kinetics of inhibition of tissue-type and urokinase-type plasminogen activator by plasminogen activator inhibitor type 1 and type 2. Eur J Biochem 175:33–39

    Article  PubMed  CAS  Google Scholar 

  22. Stief TW, Aab A, Heimburger N (1988) Oxidative inactivation of purified α2-antiplasmin, antithrombin III, and C 1-inhibitor. Thromb Res 49:581–589

    Article  PubMed  CAS  Google Scholar 

  23. Wiman B, Collen D (1978) On the kinetics of the reaction between human antiplasmin and plasmin. Eur J Biochem 84:573–578

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. M. Ries
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Zenker
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Klinge
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. R. Rauch
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. H. Keuper
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. D. Harms
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Abteilung für Angiologie, Universitätsklinikum, Theodor-Stern-Kai 7, D-60590, Frankfurt am Main, Deutschland

    Inge Scharrer

  2. Hämostaseologische Abteilung, Med. Univ.-Klinik Innenstadt, Ziemssenstraße 1a, D-80336, München, Deutschland

    Wolfgang Schramm

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Ries, M., Zenker, M., Klinge, J., Rauch, R., Keuper, H., Harms, D. (1996). Besonderheiten der Plasminogenaktivierung von Neugeborenen mit und ohne oxidative Inaktivierung von α 2-Antiplasmin. In: Scharrer, I., Schramm, W. (eds) 25. Hämophilie-Symposion Hamburg 1994. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79648-7_66

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-79648-7_66

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-59103-0

  • Online ISBN: 978-3-642-79648-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation