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In Situ Expression von Zelladhäsionsmolekül P-Selektin bei M. Crohn und Colitis Ulcerosa

In Situ Expression of Cell Adhesion Molecule P-Selectin in Crohn’s disease and ulcerative Colitis

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Chirurgisches Forum ’95 für experimentelle und klinische Forschung

Part of the book series: Langenbecks Archiv für Chirurgie ((FORUMBAND,volume 95))

Zusammenfassung

Für die Entstehung des intestinalen Entzündungsinfiltrates bei M. Crohn (MC) und Colitis ulcerosa (CU) müssen zirkulierende Zellen an der Darmgefäßwand anheften und in das Gewebe migrieren. Diese Adhäsion wird durch Zelladhäsionsmoleküle vermittelt [1, 2], unter denen insbesondere endotheliales P-Selektin die ersten Schritte des lockeren Kontaktes zum Gefäßendothel reguliert [3,4] und somit an der Entstehung des Entzündungsinfiltrates bei MC und CU beteiligt sein könnte.

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Author information

Authors and Affiliations

  1. Chirurgische Universitätsklinik, Kirschnerstr. 1, D-69120, Heidelberg, Deutschland

    Dr. med. G. Schürmann & C. Herfarth

  2. Department of Histochemistry, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK

    A. Bishop, P. Facer & J. Polak

Authors
  1. Dr. med. G. Schürmann
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  2. A. Bishop
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  3. P. Facer
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  4. J. Polak
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  5. C. Herfarth
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Editor information

Editors and Affiliations

  1. Chirurgische Klinik I, Klinikum der Universität Ulm, Steinhövelstraße 9, D-89075, Ulm, Deutschland

    Hans G. Beger

  2. Berufsgenossenschaftliche Unfallklinik Duisburg-Buchholz, Großenbaumer Allee 250, D-47249, Duisburg, Deutschland

    G. Hierholzer

  3. Abteilung Experimentelle Chirurgie, Christian-Albrechts-Universität Kiel, Arnold-Heller-Straße 7, D-24105, Kiel, Deutschland

    J. Seifert

  4. Klinik für Allgemeine Chirurgie und Thoraxchirurgie, Christian-Albrechts-Universität Kiel, Arnold-Heller-Straße 7, D-24105, Kiel, Deutschland

    J. Seifert

  5. Steinhölzle 16, D-89198, Westerstetten, Deutschland

    W. Hartel

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© 1995 Springer-Verlag Berlin Heidelberg

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Schürmann, G., Bishop, A., Facer, P., Polak, J., Herfarth, C. (1995). In Situ Expression von Zelladhäsionsmolekül P-Selektin bei M. Crohn und Colitis Ulcerosa. In: Beger, H.G., Hierholzer, G., Seifert, J., Hartel, W. (eds) Chirurgisches Forum ’95 für experimentelle und klinische Forschung. Langenbecks Archiv für Chirurgie, vol 95. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79621-0_133

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  • DOI: https://doi.org/10.1007/978-3-642-79621-0_133

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-59036-1

  • Online ISBN: 978-3-642-79621-0

  • eBook Packages: Springer Book Archive

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