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Infektionsbiologie, Epidemiologie und Diagnostik der dermatotropen Herpesviren

  • H. W. Doerr
  • H. Rabenau
Chapter
Part of the HNO Praxis Heute book series (HNO, volume 15)

Zusammenfassung

Das Herpes-simplex-Virus (HSV) mit 2 Typen, das Herpes-zoster- bzw. Varicella-Zoster-Virus (VZV), das Zytomegalievirus (CMV), das Epstein-Barr-Virus (EBV) und die neu entdeckten Herpesviren hominis (HHV) 6 und 7 bilden gemeinsam die Gruppe der humanspezifischen Herpesviren (Tabelle 1). Auch im Tierreich sind Herpesviren speziesspezifisch weit verbreitet und werden in der Familie der Herpesviridae zusammengefaßt.

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Literatur

  1. Aurelius E, Johansson B, Sköldenberg B, Forsgren M (1993) Encephalitis in immunocompetent patients due to herpes simplex virus type 1 or 2 as determined by type-specific polymerase chain reaction and antibody assays of cerebrospinal fluid. J Med Virol 39:179–186PubMedCrossRefGoogle Scholar
  2. Bahrdt B, Rabenau H, Weber B, Eibner J, Doerr HW (1992) Prävalenz Herpes- simplex-Virus-Typ-2-spezifischer Antikörper bei Personen mit unterschiedlichem Infektionsrisiko. Z Hautkr 67(1): 56–58Google Scholar
  3. Bastian FO (1972) Herpes virus hominis: Isolation from human trigenial ganglion. Science 178:306–307PubMedCrossRefGoogle Scholar
  4. Breinig MK, Kingsley RJE, Freemann DJ, Moto H (1990) Epidemiology of genital herpes in Pittsburgh. Serologic, sexual and racial correlates of apparent and inapparent herpes simplex infections. J Infect Dis 162:299–305PubMedCrossRefGoogle Scholar
  5. Bryson Y, Dillon M, Bernstein DI, Radolf J et al. (1993) Risk of acquisition of genital herpes simplex virus type 2 in sex partners of persons with genital herpes: a prospective couple study. J Infect Dis 167:942–946PubMedCrossRefGoogle Scholar
  6. Corey L, Adams H, Brown A, Holmes K (1983) Genital herpes simplex virus infection: clinical manifestations, course and complications. Ann Intern Med 98:958–963PubMedGoogle Scholar
  7. Croen KD (1988) Latency and the consequence of reactivation of the varicella-zoster-virus. Ann Intern Med 108:221–237PubMedGoogle Scholar
  8. Croen KD, Ostrove JM, Dragovic L, Straus SE (1991) Characterization of herpes simplex virus type 2 latency-associated transcription in human sacral ganglia and in cell culture. J Infect Dis 163:23–28PubMedCrossRefGoogle Scholar
  9. Dannenmaier B, Alle W, Hofer W, Lorenz D et al. (1985) Incidences of antibodies to hepatitis B, herpes simplex and cytomegalovirus in prostitutes. Zbl Bakt Hyg A 259:275–283Google Scholar
  10. Davis BDT, Dulbecco R, Eisen HN, Giusberg HS (1990) Microbiology, 4th edn. J. B. Lippincott, PhiladelphiaGoogle Scholar
  11. Doerr HW (1987) Virologie des Herpes zoster. In: Gross D, Thomalske G, Schmitt E (Hrsg) Schmerzkonferenz, Bd 5. Fischer, Stuttgart New York, S 1–14Google Scholar
  12. Doerr HW (1989) Tumor und Viren. In: Wannagat L (Hrsg) Onkologie. Tumoren des Verdauungstraktes. 2. Bad Mergentheimer Onkologisches Gespräch. Thieme, Stuttgart New YorkGoogle Scholar
  13. Doerr HW, Haas R, Mross F, Baron M (1975) Quantitativer und virusspezifischer IgM-Nachweis in Nabelschnurblut Neugeborener. Immun Infekt 6:278–280Google Scholar
  14. Doerr HW, Lehmair H, Schmitz H, Kampa D, Luthardt T (1977) Simple mathematical deductions in the seroepidemiology of viral infections. I. Herpes group (herpesvirus hominis, varizella-zoster-virus, cytomegalovirus, epstein-barr-vi- rus). Zbl Bakt I Abt Org A 238:149–164Google Scholar
  15. Doerr HW, Braun R, Munk K (1985) Human cytomegalovirus infection: Recent developments in diagnosis and epidemiology. Klin Wochensch 63:241–251CrossRefGoogle Scholar
  16. Doerr HW, Renschler M, Scheifler G (1987) Serologic detection of active infections with humanherpes virus (CMV, EBV, HSV, VZV): Diagnostic potential of IgA class and IgG subclass-specific antibodies. Infection 15:93–98PubMedCrossRefGoogle Scholar
  17. Doerr HW, Preiser W, Weber B (1993) Neue Entwicklungen in der antiviralen Chemotherapie. Immun Infekt 21:170–176Google Scholar
  18. Enders G (1976) Neutralizing serum IgM antibodies in infections with herpes simplex virus hominis. Med Microbiol Immunol 162:183–192CrossRefGoogle Scholar
  19. Enders G (1988) Infektionen und Impfungen in der Schwangerschaft. Urban & Schwarzenberg, München Wien BaltimoreGoogle Scholar
  20. Enzensberger R, Braun W, July C, Helm EB, Doerr HW (1991) Prevalence of antibodies to human herpesviruses and hepatitis virus in patients at different stages of human immunodeficiency virus (HIV) infection. Infection 19:140–145PubMedCrossRefGoogle Scholar
  21. Haas R, Doerr HW (1979/1980) Schwangerschaft und intrauterine Virusinfektion. Pädiatr Prax 22:1–14Google Scholar
  22. Heine JW, Honess RW, Cassai E, Roizman B (1974) Proteins specified by herpes simplex virus. XII. The virion polypeptides of type 1 strains. J Virol 14:640–651PubMedGoogle Scholar
  23. Höhne-Reichel G, Doerr HW (1984) Komplementbindungsreaktion (KBR) in der Virusserologie: Vergleich mit den modernen Immunassays an ausgewählten Fallbeispielen. Ärztl Lab 30:133–140Google Scholar
  24. Johnson RE, Nahmias AJ, Magder LS, Lee FK et al. (1989) A seroepidemiologic survey of the prevalence of herpes simplex virus type 2 infection in the United States. N Engl J Med 321:7–12PubMedCrossRefGoogle Scholar
  25. Kessler HH, Pierer K, Weber B, Sakrauski A etal. (1994) Detection of herpes simplex virus DNA from cerebrospinal fluid by PCR and a rapid, nonradioactive hybridization technique. J Clin Microbiol 32:1881–1886PubMedGoogle Scholar
  26. Kühn J, Biber M, Doerr HW, Braun R (1986) Diagnostik der Herpes-Simplex-Virus (HSV)-Infektion. Ärztl Lab 4:91–98Google Scholar
  27. Meier JL, Straus SE (1992) Comparative biology of latent varicella-zoster virus and herpes simplex virus infections. J Inf Dis 166:13–23CrossRefGoogle Scholar
  28. Muench R, Nassim C, Niku S, Sullivan-Bolya JZ (1986) Seroepidemiology of varicella. J Infect Dis 153:153–155PubMedCrossRefGoogle Scholar
  29. Nahmias AJ, Whitley RJ, Visintine AM, Takei CA, Alford CA (1982) Herpes simplex virus encephalitis: laboratory evaluations and their diagnostic significance. J Infect Dis 145:829–836PubMedCrossRefGoogle Scholar
  30. Nahmias AJ, Lee FK, Beckmann-Nahmias S (1990) Seroepidemiological and -sociological patterns of herpes simplex infection in the world. J Infect Dis 69:19–36Google Scholar
  31. Plotkin SA, Michelson S, Pagano JS, Papp F (1982) Pathogenesis and perention of human infection. Birth defects: original article series 20 (nr. 1), March, of Dimes Birth Defects Foundation. Alan R. Liss, New YorkGoogle Scholar
  32. Rabenau H, Eibner B, Weber B, Bahrdt B, Doerr HW (1992) Detection of herpes simplex virus (HSV) type specific antibodies by a microtechnique western blot assay. Lab Med 16:327–331Google Scholar
  33. Ragozzino MW, Melton LJ, Kurland LT, Chu CP, Perry NO (1982) Population based study of herpes zoster and its sequelae. Medicine (Baltimore) 61:310–316Google Scholar
  34. Reeves WC, Corey L, Adams HG, Vontver LA, Holmes KK (1981) Risk of recurrence after first episodes of genital herpes. N Engl J Med 305:315–319PubMedCrossRefGoogle Scholar
  35. Rogers RS, Tindall JP (1971) Geriatic herpes zoster. J Am Geriatr Soc 19:495–504PubMedGoogle Scholar
  36. Roizman B, Jenkins FJ (1985) Genetic engineering of novel genomes of large DNA viruses. Science 229:1208–1214PubMedCrossRefGoogle Scholar
  37. Roizman B, Spear PG, Kieff ED (1973) Herpes simplex viruses I and II: a biochemical definition. In: Pollard M (ed) Perspectives in virology, VIII. Academic Press, New York, p 129Google Scholar
  38. Sprössig MG, Anger G (1988) Mikrobiologisches Vademekum, 4. Aufl. Fischer, Stuttgart New YorkGoogle Scholar
  39. Stevens JG, Haarr L, Porter DD, Cook ML, Wagner EK (1988) Prominence of the herpes simplex virus latency-associated transcript in trigeminal ganglia from seropositive humans. J Infect Dis 158:117–123PubMedCrossRefGoogle Scholar
  40. Weller TH (1983) Varicella and herpes zoster: changing concepts of the natural history, control, and importance of a not-so-benign virus. N Engl J Med 309:1362–1368PubMedCrossRefGoogle Scholar
  41. Weller TH (1992) Varicella and herpes zoster: A perspective and overview. J Infect Dis 166 (Suppl 1):S 1–6Google Scholar
  42. Whitley RJ (1990a) Herpes simplex viruses. In: Fields BN, Knipe DM (eds) Virology, 2nd edn. Raven Press, New York, pp 1843–1888Google Scholar
  43. Whitley RJ (1990b) Viral encephalitis. N Engl J Med 323:242–250PubMedCrossRefGoogle Scholar
  44. Whitley RJ (1990c) Herpes simplex virus infection. In: Remington JS, Klein JO (eds) Infectious diseases of the fetus and newborn infant. Saunders, Philadelphia, pp 282–305Google Scholar
  45. Whitley RJ, Nahmias AJ, Visintine AM, Fleming CL, Alford CA (1980) A national history of herpes simplex virus infection of mother and newborn. Pediatrics 66:489–494PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • H. W. Doerr
  • H. Rabenau

There are no affiliations available

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