Follicular Dendritic Cells: Structure as Related to Function

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 201)


Follicular dendritic cells (FDC) have been noted as one of unique immunological accessory cells. They are localized within lymphoid follicles as an intricate cellular meshwork that helps to maintain follicular structure. FDC also have the capability to trap and retain antigens in the form of immune complexes on their surface for long periods, providing unprocessed antigens to germinal center B cells in the form of iccosomes (immune complex-coated bodies); In this chapter, the morphological features and the cytochemical and immunological phenotypes of FDC are reviewed and discussed within the context of recent topics and controversial issues.


Germinal Center Follicular Dendritic Cell Human Tonsil Terminal Complement Complex Dendritic Reticulum Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  1. 1.Department of PathologyYamagata University School of MedicineYamagataJapan

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