The Construction of Cell Cultures Genetically Engineered for Metabolic Competence towards Xenobiotics
Analytical tools have always played an important role for the study and understanding the complex biotransformation process. It needs technology to develop analytical tools. In this sense, gene technology is the most recent technology being applied in the construction of in vitro system useful for metabolism studies of xenobiotics. This includes cloning of genes encoding xenobiotics metabolizing enzymes, construction of recombinant expression vectors, and genetically engineering of cell cultures.
KeywordsHuman Cytochrome Recombinant Vaccinia Virus Cytochrome P450 Gene Biological Endpoint Packaging Cell Line
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