Abstract
The recently developed technology of amplification of DNA sequences by the polymerase chain reaction (1) has already proved to be a very useful tool for the analysis of variable number of tandem repeat (VNTR or minisatellites) loci for forensic purposes (2). Trimeric and tetrameric short tandem repeat (STR or microsatellites) DNA sequences are other highly polymorphic markers distributed throughout genic and extragenic regions of the human genome (3, 4). STR loci appear to be informative and promising PCR based identification systems. In fact, DNA typing based on amplification of STRs is very sensitive and allows to overcome major problems encountered in forensic practice, such as typing of minute amounts of DNA, highly degraded DNA, or mixtures of DNA from more than one individual. The high sensitivity and the increased speed of the PCR technique are two important properties for forensic analyses.
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© 1995 Springer-Verlag Berlin Heidelberg
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Pfitzinger, H., Rousselet, F., Ludes, B., Kintz, P., Tracqui, A., Mangin, P. (1995). French Caucasian Population Data for HUMTH01 and HUMFESFPS Short Tandem Repeat (STR) systems. In: Mangin, P., Ludes, B. (eds) Acta Medicinæ Legalis Vol. XLIV 1994. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79523-7_27
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DOI: https://doi.org/10.1007/978-3-642-79523-7_27
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