Post-transcriptional Control of Adenovirus Gene Expression

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 199/2)


Adenovirus genes are expressed in a defined, temporally controlled manner during the course of a lytic infection. The mechanisms responsible for this control have been the subject of intense study. These studies have shown that, although control of transcription initiation is a major determinant of the observed pattern of viral gene expression, post-transcriptional control is also crucial to a successful outcome of infection. It is these latter mechanisms which are the subject of this chapter.


Splice Site Adenovirus Type mRNA Transport Polypyrimidine Tract Late Gene Expression 
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© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  1. 1.Department of Microbiology and ImmunologyUniversity of Michigan Medical SchoolAnn ArborUSA
  2. 2.Department of Cell and Molecular BiologyKarolinska InstituteStockholmSweden
  3. 3.Department of Biological SciencesUniversity of WarwickCoventryUK

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