Expression, Nuclear Transport, and Phosphorylation of Adenovirus DNA Replication Proteins

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 199/2)


DNA tumor viruses have contributed immense wealth of knowledge in the past few years regarding the eukaryotic cellular processes involving replication, transcription, and translation. Adenoviruses (Ad) in particular have played a pioneering and significant role in the understanding of the mechanisms of many of these biological processes mainly due to the interaction of viral proteins with the host proteins during the virus life cycle. The development of the first cell-free system to study Ad DNA replication (Challberg and Kelly 1979; for reviews, see Challberg and Kelly 1989; Stillman 1989; Hay and Russell 1989) was pivotal to our current understanding of eukaryotic DNA replication.


Nuclear Transport Adenovirus Type Recombinant Vaccinia Virus Cdc2 Kinase Nuclear Localization Signal Sequence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  1. 1.Department of Biochemistry and Molecular BiologyUniversity of Kansas Medical CenterKansas CityUSA

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