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The Molecular Repertoire of Adenoviruses II pp 49–88Cite as

Expression, Nuclear Transport, and Phosphorylation of Adenovirus DNA Replication Proteins

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 199/2))

Abstract

DNA tumor viruses have contributed immense wealth of knowledge in the past few years regarding the eukaryotic cellular processes involving replication, transcription, and translation. Adenoviruses (Ad) in particular have played a pioneering and significant role in the understanding of the mechanisms of many of these biological processes mainly due to the interaction of viral proteins with the host proteins during the virus life cycle. The development of the first cell-free system to study Ad DNA replication (Challberg and Kelly 1979; for reviews, see Challberg and Kelly 1989; Stillman 1989; Hay and Russell 1989) was pivotal to our current understanding of eukaryotic DNA replication.

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  1. Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS, 66160-7421, USA

    M. Ramachandra & R. Padmanabhan

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Ramachandra, M., Padmanabhan, R. (1995). Expression, Nuclear Transport, and Phosphorylation of Adenovirus DNA Replication Proteins. In: Doerfler, W., Böhm, P. (eds) The Molecular Repertoire of Adenoviruses II. Current Topics in Microbiology and Immunology, vol 199/2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79499-5_3

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  • DOI: https://doi.org/10.1007/978-3-642-79499-5_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79501-5

  • Online ISBN: 978-3-642-79499-5

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