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Structure and Mechanism of DNA Gyrase

  • D. B. Wigley
Part of the Nucleic Acids and Molecular Biology book series (NUCLEIC, volume 9)

Abstract

DNA gyrase is a type II DNA topoisomerase found in bacteria. Since its discovery in 1976 (Geliert et al. 1976), it has been the focus of a great deal of research, from both mechanistic and medical viewpoints, and it is the purpose of this chapter to address the first of these two areas.

Keywords

Negative Supercoils Adjacent Subunit Ribose Sugar Strand Passage Supercoiling Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • D. B. Wigley
    • 1
  1. 1.Laboratory of Molecular Biophysics, Rex Richards BuildingUniversity of OxfordOxfordUK

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