Structure and Mechanism of DNA Gyrase
DNA gyrase is a type II DNA topoisomerase found in bacteria. Since its discovery in 1976 (Geliert et al. 1976), it has been the focus of a great deal of research, from both mechanistic and medical viewpoints, and it is the purpose of this chapter to address the first of these two areas.
KeywordsHydrolysis Hydroxyl Platinum Tyrosine Manganese
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