Skip to main content

Etiology of Schizophrenia: Perspectives from Childhood Psychoses

  • Conference paper
Psychotic Continuum
  • 46 Accesses

Abstract

Schizophrenic psychoses in childhood were delineated as specific psychotic disorders only in the late 1930s (Lutz 1937/1938). But the history of childhood schizophrenia starts earlier. Hermann Emminghaus, who wrote the first textbook of child psychiatry in 1887 with the title Psychic Disturbances of Childhood, describes childhood psychoses as “cerebral neurasthenia” and defines these disorders as “neuroses of the brain characterized by a reduction of cognitive abilities, mood changes, sleep disturbances and manyfold anomalies of innervation with a subacute or chronic course and different states of outcome” (Emminghaus 1887, p. 134). Emminghaus was also the first who introduced the developmental perspective into child psychiatry with special focus on psychoses. After Emil Kraepelin, at the end of the past century, first described dementia praecox (Kraepelin 1886) and Eugen Bleuler (1911) introduced the term “schizophrenia”, August Homburger stated, in his famous textbook (Homburger 1926), that childhood schizophrenia really exists and may be characterized by the following features: (a) A predominant change of the personality of the children in the direction of withdrawal, negativism, and strange and unexpected behavior.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Annell A (1963) The prognosis of psychotic syndromes in children. Acta Psychiatry Scand 39:235–241

    CAS  Google Scholar 

  • Asarnow R, Sherman T, Strandburg R (1986) The search for the psychobiological substrate of childhood onset schizophrenia. J Am Acad Child Psychiatry 26:601–604

    Google Scholar 

  • Asperger H (1989) Die “Autistischen Psychopathien” im Kindesalter. Arch Psychiatrie Nervenkrankh 117:76–136

    Article  Google Scholar 

  • Bleuler E (1911) Dementia praecox oder Gruppe der Schizophrenien. In: Aschaffenburg G (ed) Hand buch der Psychiatrie, spezieller Teil, vierte Abteilung. Deuticke, Wien- Leipzig

    Google Scholar 

  • Bleuler E (1972) Die schizophrenen Geistesstörungen. Thieme, Stuttgart

    Google Scholar 

  • Burd L, Kerbeshian J (1987) A North Dakota prevalence study of schizophrenia presenting in childhood. J Am Acad Child Adolesc Psychiatry 26:347–350

    Article  PubMed  CAS  Google Scholar 

  • Caplan R, Guthrie D, Fish B, Tanguay PE, David-Lando G (1989) The Kiddy Formal Thought Disorder Rating Scale (K-FTDS). Clinical assessment, reliability, and validity. J Am Acad Child Adolesc Psychiatry 28:208–216

    Article  Google Scholar 

  • Caplan R, Guthrie D, Foy JG (1992) Communication deficits and formal thought disorder in schizophrenic children. J Am Acad Child Adolesc Psychiatry 31:151–159

    Article  PubMed  CAS  Google Scholar 

  • Castle DJ, Murray RN (1991) The neurodevelopmental basis of sex differences in schizophrenia. Psychol Med 21:565–575

    Article  PubMed  CAS  Google Scholar 

  • Cornblatt WA, Risch N, Faris G (1988) The Continuous Performance Test, Identical Pairs Version (CPT-IP). I. New findings about sustained attention in normal families. Psychiatry Res 26:223–238

    Article  PubMed  CAS  Google Scholar 

  • Cornblatt BA, Lenzenweger MF, Dworkin RH, Erlenmeyer-Kimling L (1992) Childhood attentional dysfunction predicts social deficits in unaffected adults at risk for schizophrenia. Br J Psychiatry 161 [Suppl 18]:59–64

    Google Scholar 

  • Eggers C (1967) Prognose und Verlauf kindlicher und präpuberaler Schizophrenien. Med. Dissertation, Marburg

    Google Scholar 

  • Eggers C (1973) Verlaufs weisen kindlicher und präpuberaler Schizophrenien. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Emminghaus H (1887) Die psychischen Störungen des Kindesalters. Laupp, Tübingen

    Google Scholar 

  • Fish B (1977) Neurobiological antecedents of schizophrenia in children: evidence for an inherited, congenital neurointegrative defect. Arch Gen Psychiatry 34:1297–1313

    PubMed  CAS  Google Scholar 

  • Fish B, Marcus J, Hans SL, Auerbach JG, Purdue S (1992) Infants at risk for schizophrenia: sequelae of genetic neurointegrative defect. Arch Gen Psychiatry 49:221–235

    PubMed  CAS  Google Scholar 

  • Group for the Advancement of Psychiatry (1966) Psychopathological disorders in childhood: theoretical considerations and a proposed classification. GAP, New York

    Google Scholar 

  • Häfner H, Riecher H, Maurer K, Meissner S, Schmidtke A, Fätkenheuer B, Löffler W, Anderheiden W (1990) Ein Instrument zur retrospektiven Einschätzung des Erkrankungsbeginns bei Schizophrenie (Instrument for the retrospective assessment of the onset of schizophrenia - “IRAOS”) - Entwicklung und erste Ergebnisse. Z Klin Psychologie 19:230–255

    Google Scholar 

  • Häfner H, Riecher-Rössler A, Hambrecht M, Maurer K, Meissner S, Schmidtke A, Fätkenheuer B, Löffler W, Anderheiden W (1992a) IRAOS: an instrument for the assessment of onset and early course of schizophrenia. Schizophrenia Res 6:209–223

    Article  Google Scholar 

  • Häfner H, Riecher-Rössler A, Maurer K, Fätkenheuer B, Löffler W (1992b) First onset and early symptomatology of schizophrenia. Eur Arch Psychiatry Clin Neurosci 242:109–11

    Article  PubMed  Google Scholar 

  • Holzman PS (1983) Smooth pursuit eye movements in psychopathology. Schizophr Bull 9:33–36

    PubMed  CAS  Google Scholar 

  • Homburger A (1926) Vorlesungen über Psychopathologie des Kindesalters. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Kanner L (1943) Autistic disturbances of affective contact. Nerv Child 2:217–250

    Google Scholar 

  • Kanner L (1957) Child psychiatry, 3rd edn. Blackwell, Oxford

    Google Scholar 

  • Karno M, Norquist GS (1989) Schizophrenia: epidemiology. In: Kaplan HI, Saddock BJ (eds) Comprehensive textbook of psychiatry, 5th edn, vol I. Williams & Wilkins, Baltimore

    Google Scholar 

  • Kolvin E, Ounsted C, Humphrey M, McNay A (1971a) Six studies in the childhood psychoses. II. The phenomenology of childhood psychoses. Br J Psychiatry 118:385–395

    Article  PubMed  CAS  Google Scholar 

  • Kolvin E, Ounsted C, Richardson LM, Garside RF (1971b) Six studies in the childhood psychoses. III. The family and social background in childhood psychoses. Br J Psychiatry 118:396–402

    Article  PubMed  CAS  Google Scholar 

  • Kolvin E, Garside RF, Kidd JSH (1971c) Six studies in the childhood psychoses. IV. Parental personality and attitude and childhood psychoses. Br J Psychiatry 118:403–406

    Article  PubMed  CAS  Google Scholar 

  • Kolvin E, Ounsted C, Roth M (1971d) Six studies in the childhood psychoses. V. Cerebral dysfunction and childhood psychoses. Br J Psychiatry 118:407–414

    Article  PubMed  CAS  Google Scholar 

  • Kraepelin E (1886) Psychiatrie. Ein Lehrbuch für Studierende und Ärzte. Barth, Leipzig

    Google Scholar 

  • Lenzenweger MF, Loranger AW (1989) Detection of familiar schizophrenia using a psychometric measure of schizotypy. Arch Gen Psychiatry 46:902–907

    PubMed  CAS  Google Scholar 

  • Leonhard K (1986) Die Aufteilung der endogenen Psychosen und ihre differenzierte Ätiologie. 6. Auflage. Akademie-Verlag, Berlin

    Google Scholar 

  • Lutz J (1937/1938) Über Schizophrenie im Kindesalter. Schweiz Arch Neurol Neurochir Psychiatr 39:335–372, 40:141–163

    Google Scholar 

  • Lutz J (1972) Kinderpsychiatrie. Rotapfel, Zürich

    Google Scholar 

  • Markus J (1974) Cerebral functioning in offspring of schizophrenics: a possible genetic factor. Int J Ment Health 3:57–73

    Google Scholar 

  • Martin M (1991) Der Verlauf der Schizophrenie im Jugendalter unter Rehabilitationsbedingungen. Enke, Stuttgart

    Google Scholar 

  • Martin ME, Chapman LJ (1982) Communication effectiveness in psychosis-prone college students. J Abnorm Psychol 91:420–425

    Article  PubMed  CAS  Google Scholar 

  • Remschmidt H (1988) Schizophrene Psychosen im Kindesalter. In: Kisker KP, Lauter H, Meyer J-E, Müller C, Strömgren E (eds) Psychiatrie der Gegenwart. Bd. 7: Kinder- und Jugendpsychiatrie. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Remschmidt H (1993) Schizophrenic psychoses in children and adolescents. Triangle 32:15–24

    Google Scholar 

  • Remschmidt H, Martin M (1992) Die Therapie der Schizophrenie im Jugendalter. Dtsch Arztebl 89:387–396

    Google Scholar 

  • Remschmidt H, Martin M, Albrecht G, Gerlach G, Rühl D (1988) Der Voraussagewert des Initialbefundes für den mittelfristigen Rehabilitationsverlauf bei jugendlichen Schizophrenen. Nervenarzt 59:471–476

    PubMed  CAS  Google Scholar 

  • Remschmidt H, Martin M, Schulz E, Gutenbrunner C, Fleischhaker C (1991) The concept of positive and negative schizophrenia in child and adolescent psychiatry. In: Marneros A, Andreasen NC, Tsuang MT (eds) Negative versus positive schizophrenia. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Remschmidt H, Schulz E, Martin M (1992) Die Behandlung schizophrener Psychosen in der Adoleszenz mit Clozapin (Leponex). In: Naber D, Müller-Spahn F (eds) Clozapin. Pharmakologie und Klinik eines atypischen Neuroleptikums. Eine kritische Bestandsaufnahme. Schattauer, Stuttgart

    Google Scholar 

  • Remschmidt H, Schulz E, Martin M, Warnke A, Trott G-E (1994) Childhood-onset schizophrenia: history of the concept and recent studies. Schizophrenia Bulletin 20:727–745

    PubMed  CAS  Google Scholar 

  • Rutter M, Lockyer L, Greenfield D (1967) A five to fifteen-year follow-up study of infantile psychoses. II. Social and behavioural outcome. Br J Psychiatry 113:1189–1199

    Google Scholar 

  • Rutter ML, Shaffer D, Sturge C (1976) A guide to a multi-axial classification scheme for psychiatric disorders in childhood and adolescence. Frowde, London

    Google Scholar 

  • Siefen G, Remschmidt H (1986) Behandlung mit Clozapin bei schizophrenen Jugendlichen. Z Kinder Jugendpsychiatr 14:245–257

    PubMed  CAS  Google Scholar 

  • Siever LJ, Silverman J, Horvat TB (1990) Increased morbid risk for schizophrenia- related disorders in relatives of schizotypal personality disordered patients. Arch Gen Psychiatry 47:634–670

    PubMed  CAS  Google Scholar 

  • Stutte H (1969) Psychosen des Kindesalters. In: Schmid F, Asperger H (eds) Neurologie - Psychologie - Psychiatrie. (Handbuch der Kinderheilkunde, Bd. VIII/1). Springer, Berlin Heidelberg New York

    Google Scholar 

  • Volkmar FR, Cohen DJ (1991) Comorbid association of autism and schizophrenia. J Am Acad Child Adolesc Psychiatry 148:1705–1707

    CAS  Google Scholar 

  • Weiner IB (1982) Child and adolescent psychopathology. Wiley, New York

    Google Scholar 

  • Werry JS (1992) Child and adolescent (early onset) schizophrenia: a review in the light of DSM-III-R. J Autism Devel Disord 22:601–624

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Remschmidt, H., Martin, M., Schulz, E., Trott, GE. (1995). Etiology of Schizophrenia: Perspectives from Childhood Psychoses. In: Marneros, A., Andreasen, N.C., Tsuang, M.T. (eds) Psychotic Continuum. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79485-8_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-79485-8_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79487-2

  • Online ISBN: 978-3-642-79485-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics