Das Dermatofibrosarcoma protuberans (DFSP). Schwierigkeiten in Diagnostik und Möglichkeiten der Therapie

  • A. Petres
  • S. Wiemers
  • W. Vanscheidt
  • E. Schopf
Conference paper
Part of the Fortschritte der operativen und onkologischen Dermatologie book series (OP.DERMATOLOGIE, volume 9)

Zusammenfassung

Das Dermatofibrosarcoma protuberans (DFSP) ist ein Tumor intermediärer Dignität. Er zeichnet sich durch lokal infiltrativ-destruktives Wachstum, hohe Rezidivneigung und geringe Me-tastasierungstendenz aus. Die Ätiologie des Tumors ist nicht bekannt. Er gehört zur Gruppe der fibrohistiozytären Tumoren; neuere Untersuchungen leiten die Histogenese von den erstmals von Nickoloff beschriebenen CD 34-positiven Spindelzellen der Haut ab. Die histologi-sche Differentialdiagnose hat neben den eigentlichen fibrohistiozytären Tumoren auch spin-delzellige Tumoren anderer Ursprungsgewebe und reaktive Veränderungen zu berücksichtigen. Neue diagnostische Möglichkeiten ergeben sich mit der Verwendung des anti-CD 34-Antikörpers. Die chirurgische Therapie in Form einer großzügigen Exzision unter Mitnahme der subtumoralen Muskelfaszie stellt die einzige effektive Therapiemethode dar.

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© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • A. Petres
  • S. Wiemers
  • W. Vanscheidt
  • E. Schopf

There are no affiliations available

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