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Estrogenic Effects of Some Xenobiotics

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Toxicology in Transition

Part of the book series: Archives of Toxicology ((TOXICOLOGY,volume 17))

Abstract

While investigating the estrogenic properties of the pesticide Fosmet administered to neonatal rats we found that a 10% emulsion concentrate of Tween 80 can increase the mean relative weight of the uterus and cause changes in the endometrium that are characteristic of the action of estrogens (Gajdováet al., 1988). In the rats exposed to Tween 80 we found a significant prolongation of the oestrous cycle and persistent vaginal estrus in adulthood (Vargová et al., 1990). Similar changes after the application of some substances with estrogenic effect were; described by Bulger and Kupfer (1985).

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© 1995 Springer-Verlag Berlin Heidelberg

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Vargová, M., Gajdová, M., Jakubovský, J., Wsólová, L. (1995). Estrogenic Effects of Some Xenobiotics. In: Degen, G.H., Seiler, J.P., Bentley, P. (eds) Toxicology in Transition. Archives of Toxicology, vol 17. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79451-3_12

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  • DOI: https://doi.org/10.1007/978-3-642-79451-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79453-7

  • Online ISBN: 978-3-642-79451-3

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