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Cytokines and Neuroendocrine Hormones as Mediators of Cutaneous Immunity and Inflammation

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Abstract

Cytokines are low molecular weight proteins that are produced transiently by almost any eukaryotic cell. They exert their biological activities via interaction with specific cell surface receptors, which are expressed in relatively low numbers. There is evidence for a network of interacting cytokines, as they usually have multiple overlapping activities [10]. Cytokines may induce each other or interfere with the expression of their receptors and thus can affect cell function in a synergistic, additive or antagonistic way. The cytokine family consists of interleukins, chemokines, tumor necrosis factors, colony-stimulating factors, interferons, growth factors and suppressor factors. In this review mainly cytokines of special significance for the regulation of cutaneous immune and inflammatory responses will be discussed, whereas most other cytokines and mediators will only be mentioned briefly.

Keywords

  • Leukemia Inhibitory Factor
  • Immunol Today
  • Human Dermal Microvascular Endothelial Cell
  • Contact Hypersensitivity
  • Neuroendocrine Hormone

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Luger, T.A., Schwarz, T. (1995). Cytokines and Neuroendocrine Hormones as Mediators of Cutaneous Immunity and Inflammation. In: Eibl, M.M., Huber, C., Peter, H.H., Wahn, U. (eds) Symposium in Immunology IV. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79446-9_1

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