Cytokines and Neuroendocrine Hormones as Mediators of Cutaneous Immunity and Inflammation

  • T. A. Luger
  • T. Schwarz
Conference paper

Abstract

Cytokines are low molecular weight proteins that are produced transiently by almost any eukaryotic cell. They exert their biological activities via interaction with specific cell surface receptors, which are expressed in relatively low numbers. There is evidence for a network of interacting cytokines, as they usually have multiple overlapping activities [10]. Cytokines may induce each other or interfere with the expression of their receptors and thus can affect cell function in a synergistic, additive or antagonistic way. The cytokine family consists of interleukins, chemokines, tumor necrosis factors, colony-stimulating factors, interferons, growth factors and suppressor factors. In this review mainly cytokines of special significance for the regulation of cutaneous immune and inflammatory responses will be discussed, whereas most other cytokines and mediators will only be mentioned briefly.

Keywords

Lymphoma Cysteine Immobilization Interferon Neutropenia 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • T. A. Luger
  • T. Schwarz

There are no affiliations available

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