Chicago Experience of Intestinal Strictures and Inflammatory Bowel Disease

  • J. D. Lloyd-Still


Factors Involved in Reported Cases of Colonic Strictures

  1. 1.

    Associated with high-strength lipase enzymes (>20000 units).

  2. 2.

    Associated with excessive dosage (>18000 units/kg/meal).

  3. 3.

    Associated with prolonged duration of administration (over 6 months).

  4. 4.

    Associated with age group 2-5 years.

  5. 5.

    Associated with meconium ileus in 50% of cases in the U.S., but not in Europe.

  6. 6.

    Restricted to cystic fibrosis patients.



Permeability Europe Lipase Luminal Peri 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Smyth RL, van Velzen D, Smyth AR, etal. (1994) Strictures of ascending colon in cystic fibrosis and high-strength pancreatic enzymes. Lancet 343:85–86PubMedCrossRefGoogle Scholar
  2. 2.
    Bjarnason I, Peters TJ (1989) Intestinal permeability, non-steroidal anti-inflammatory drug enteropathy and inflammatory bowel disease: an overview. Got Festschrift 22–28Google Scholar
  3. 3.
    Lloyd-Still JD (1994) Crohn’s disease and cystic fibrosis. Digestive Diseases and Sciences 39 (4):880–885PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • J. D. Lloyd-Still
    • 1
  1. 1.ChicagoUSA

Personalised recommendations