Functional MRI of human motor cortex using a conventional MRI system

  • M. Sasahira
  • M. Niiro
  • A. Haruzono
  • W. Hirakawa
  • T. Asakura
  • T. Fujimoto
Conference paper

Abstract

Functional MRI of the brain was performed with motor task activation in normal volunteers and a patient with a meningioma using conventional FLASH sequences and a 2.0 T MRI system. A bright signal intensity in the motor cortex was observed in all cases. In the single-slice studies, the right-sided finger task produced an increase of 6.67 ± 4.36% in the signal intensity of the left motor cortex, while the left-sided finger task increased the signal by 6.09 ± 3.34% in the right motor cortex. There were no significant differences between the sides. In the multiple-slice studies, the activated motor cortex was also seen as a bright signal. Preoperative mapping of the meningioma showed that the motor cortex was displaced posteriorly by the tumour. Our clinical study demonstated the possibility of functional MRI with a standard MRI system and conventional FLASH sequences. Useful information can be obtained by preoperative mapping of the motor cortex.

Key words

Functional magnetic resonance imaging Motor cortex 

References

  1. 1.
    Ogawa S, Lee TM, Kay AR et al. (1990) Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci USA 87:9868–9872.PubMedCrossRefGoogle Scholar
  2. 2.
    Thulborn KR, Waterton JC, Styles P et al. (1982) Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochem Biophys Acta 14:265–270.Google Scholar
  3. 3.
    Turner R, LeBihan D, Moonen CT et a. (1991) Echo-planar time course MRI of cat brain oxygenation changes. Magn Reson Med 22:159–166.PubMedCrossRefGoogle Scholar
  4. 4.
    Ogawa S, Tank DW, Menon R et al. (1992) Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 89:5951–5955.PubMedCrossRefGoogle Scholar
  5. 5.
    Bandettini PA, Wong EC, Hinks RS et al. (1992) Time course EPI of human brain function during task activation. Magn Reson Med 25: 390–397.PubMedCrossRefGoogle Scholar
  6. 6.
    Blamire AM, Ogawa S, Ugurbil K et al. (1992) Dynamic mapping of visual cortex by high-speed magnetic resonance imaging. Proc Natl Acad Sci USA 89: 11069–11073.PubMedCrossRefGoogle Scholar
  7. 7.
    Kwong KK, Belliveau JW, Chesler DA et al. (1992) Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89: 5675–5679.PubMedCrossRefGoogle Scholar
  8. 8.
    Jack CR Jr, Thompson RM, Butts RK et al. (1993) Sensory motor cortex: correlation of presurgical mapping with functional MR imaging and inversive cortical mapping. Radiology 190: 85–92.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • M. Sasahira
    • 1
  • M. Niiro
    • 2
  • A. Haruzono
    • 1
  • W. Hirakawa
    • 1
  • T. Asakura
    • 1
  • T. Fujimoto
    • 2
  1. 1.Department of Neurosurgery, Faculty of MedicineKagoshima UniversityKagoshimaJapan
  2. 2.South Japan Health Science CentreMiyakonojoJapan

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