Abstract
Functional MRI of the brain was performed with motor task activation in normal volunteers and a patient with a meningioma using conventional FLASH sequences and a 2.0 T MRI system. A bright signal intensity in the motor cortex was observed in all cases. In the single-slice studies, the right-sided finger task produced an increase of 6.67 ± 4.36% in the signal intensity of the left motor cortex, while the left-sided finger task increased the signal by 6.09 ± 3.34% in the right motor cortex. There were no significant differences between the sides. In the multiple-slice studies, the activated motor cortex was also seen as a bright signal. Preoperative mapping of the meningioma showed that the motor cortex was displaced posteriorly by the tumour. Our clinical study demonstated the possibility of functional MRI with a standard MRI system and conventional FLASH sequences. Useful information can be obtained by preoperative mapping of the motor cortex.
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References
Ogawa S, Lee TM, Kay AR et al. (1990) Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci USA 87:9868–9872.
Thulborn KR, Waterton JC, Styles P et al. (1982) Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochem Biophys Acta 14:265–270.
Turner R, LeBihan D, Moonen CT et a. (1991) Echo-planar time course MRI of cat brain oxygenation changes. Magn Reson Med 22:159–166.
Ogawa S, Tank DW, Menon R et al. (1992) Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 89:5951–5955.
Bandettini PA, Wong EC, Hinks RS et al. (1992) Time course EPI of human brain function during task activation. Magn Reson Med 25: 390–397.
Blamire AM, Ogawa S, Ugurbil K et al. (1992) Dynamic mapping of visual cortex by high-speed magnetic resonance imaging. Proc Natl Acad Sci USA 89: 11069–11073.
Kwong KK, Belliveau JW, Chesler DA et al. (1992) Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89: 5675–5679.
Jack CR Jr, Thompson RM, Butts RK et al. (1993) Sensory motor cortex: correlation of presurgical mapping with functional MR imaging and inversive cortical mapping. Radiology 190: 85–92.
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© 1995 Springer-Verlag Berlin Heidelberg
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Sasahira, M., Niiro, M., Haruzono, A., Hirakawa, W., Asakura, T., Fujimoto, T. (1995). Functional MRI of human motor cortex using a conventional MRI system. In: Takahashi, M., Korogi, Y., Moseley, I. (eds) Proceedings of the XV Symposium Neuroradiologicum. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79434-6_9
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DOI: https://doi.org/10.1007/978-3-642-79434-6_9
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