Noninvasive characterisation of intracranial tumours by in vivo proton magnetic resonance spectroscopy

  • M. Harada
  • M. Tanouchi
  • H. Nishitani
  • H. Miyoshi
  • K. Bandou
  • S. Kannuki
Conference paper

Abstract

We studied the possibility of tissue characterisation of intracranial tumours by localised proton magnetic resonance spectroscopy (1H-MRS). Twenty-six newly diagnosed tumours were examined by in vivo 1H-MRS. The N-acetyl aspartate/choline (NAA/Cho ratio of grade 2 astrocytomas was relatively higher than that of those of grade 4. The choline/creatine (Cho/Cr) ratio of meningiomas was considerably higher than that of gliomas of all grades. We found only 2 cases of ependymoma, and the Cho/Cr ratio in both was lower than that in other gliomas. We considered that 1 H-MRS can be used to differentiate grade 2 from grade 4 in most cases of astrocytoma by the NAA/Cho ratio, though a few cases will overlap. Meningioma can easily be separated from glioma, and the results of our study suggest that ependymoma has a characteristic pattern.

key words

Proton magnetic resonance spectroscopy Brain tumour Meningioma Ependymoma 

References

  1. 1.
    Harada M, Tanouchi M, Miyoshi H, Nishitani H, Kannuki S (1995) Brain abscess observed by localized proton magnetic resonance spectroscopy. Magn Reson Imaging (in press)Google Scholar
  2. 2.
    Gill SS, Thomas DGT, Bruggen NV, Gadian DG, Peden CJ, Bell JD, Cox IJ, Menon DK, Iles RA, Bryant DJ, Coutts GA (1990) Proton MR spectroscopy of intracranial tumours: In vivo and In vitro studies. J Comput Assist Tomogr 14: 497–504.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • M. Harada
    • 1
  • M. Tanouchi
    • 1
  • H. Nishitani
    • 1
  • H. Miyoshi
    • 2
  • K. Bandou
    • 3
  • S. Kannuki
    • 3
  1. 1.Department of Radiology, School of MedicineUniversity of TokushimaTokushima, 770Japan
  2. 2.Department of Radiological Technology, School of Medical ScienceUniversity of TokushimaTokushima, 770Japan
  3. 3.Department of Neurosurgery, School of MedicineUniversity of TokushimaTokushima, 770Japan

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