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Noninvasive characterisation of intracranial tumours by in vivo proton magnetic resonance spectroscopy

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Abstract

We studied the possibility of tissue characterisation of intracranial tumours by localised proton magnetic resonance spectroscopy (1H-MRS). Twenty-six newly diagnosed tumours were examined by in vivo 1H-MRS. The N-acetyl aspartate/choline (NAA/Cho ratio of grade 2 astrocytomas was relatively higher than that of those of grade 4. The choline/creatine (Cho/Cr) ratio of meningiomas was considerably higher than that of gliomas of all grades. We found only 2 cases of ependymoma, and the Cho/Cr ratio in both was lower than that in other gliomas. We considered that 1 H-MRS can be used to differentiate grade 2 from grade 4 in most cases of astrocytoma by the NAA/Cho ratio, though a few cases will overlap. Meningioma can easily be separated from glioma, and the results of our study suggest that ependymoma has a characteristic pattern.

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References

  1. Harada M, Tanouchi M, Miyoshi H, Nishitani H, Kannuki S (1995) Brain abscess observed by localized proton magnetic resonance spectroscopy. Magn Reson Imaging (in press)

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  2. Gill SS, Thomas DGT, Bruggen NV, Gadian DG, Peden CJ, Bell JD, Cox IJ, Menon DK, Iles RA, Bryant DJ, Coutts GA (1990) Proton MR spectroscopy of intracranial tumours: In vivo and In vitro studies. J Comput Assist Tomogr 14: 497–504.

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© 1995 Springer-Verlag Berlin Heidelberg

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Harada, M., Tanouchi, M., Nishitani, H., Miyoshi, H., Bandou, K., Kannuki, S. (1995). Noninvasive characterisation of intracranial tumours by in vivo proton magnetic resonance spectroscopy. In: Takahashi, M., Korogi, Y., Moseley, I. (eds) Proceedings of the XV Symposium Neuroradiologicum. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79434-6_72

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  • DOI: https://doi.org/10.1007/978-3-642-79434-6_72

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79436-0

  • Online ISBN: 978-3-642-79434-6

  • eBook Packages: Springer Book Archive

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