Quantitating blood flow by digital angiography: a gold standard?

  • G. du Boulay
  • J. N. H. Brunt
  • A. Wallis
Conference paper

Abstract

Volume blood flow is measurable from digital data acquired during angiography and can be plotted as it changes throughout a cardiac cycle. The method has now been introduced on a trial basis during some carotid and vertebral studies at the National Hospital, Queen Square. The results, which fall numerically within the range predicted by 133Xe cerebral blood flow methods, reveal patterns consistent with pathological conditions. It is suggested that the method could provide a Standard to assist and calibrate ultrasonic flow measurement and magnetic resonance quantitative angiography.

key words

Digital angiography Blood flow 

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References

  1. 1.
    Brunt JNH, Boulay GH du, Wallis A, Wicks DAG (1991) Fluid flow measurement in vessels from digital subtraction angiography video recordings. Neuroradiology 33 [Suppl]: 456–458.Google Scholar
  2. 2.
    Brunt JNH, Hawkes DJ, Seifalian AM, Boulay GH du, Colchester AFC, Wallis A (1992) The measurement of blood flow waveforms X-ray angiography, pts 1,2. Proc Inst Mech Eng 206: 73–85; 87-91.Google Scholar
  3. 3.
    Colchester ACF, Hawkes DJ, Brunt JNH, Boulay GH du, Wallis A (1986) Pulsatile blood flow measurements with the aid of 3-D reconstruction from dynamic angiographic recordings. In: Bacharach ST (ed) Information processing in medical imaging. Martinus Nijhoff, Dordrecht, pp 247–265.CrossRefGoogle Scholar
  4. 4.
    Seifalian AM, Hawkes DJ, Colchester AFC, Hobbs KE (1989) A new algorithm for deriving pulsatile blood flow waveforms, tested using simulated dynamic angiographic data. Neuroradiology 31: 263–269.PubMedCrossRefGoogle Scholar
  5. 5.
    Wilkinson TMS, Bull JWD, Boulay GH du, Marshall I, Ross J, Russell RW, Symon L (1969) Regional blood flow in the normal cerebral hemisphere. J Neurol Neurosurg Psychiat 32: 367–378.PubMedCrossRefGoogle Scholar
  6. 6.
    Munck O, Barenholdt O, Busch (1968) Cerebral blood flow in organic dementia, measured with the xenon-133 desaturation method. Scand J Lab Clin Invest [Suppl] 102.Google Scholar
  7. 7.
    Winkler P, Helmke K (1990) Major pitfalls in Doppler investigations with particular reference to the cerebral vascular system. 1. Sources of error, resulting pitfalls and measures to prevent errors. Pediatr Radiol 20: 219.PubMedCrossRefGoogle Scholar
  8. 8.
    Matsumoto M, Sekimoto H, Griya Y, Matsumoto M, Tsuchia H, Takasaki M, Takizawa S (1992) Simultaneous cardio-cerebral ultrasonic measurement technique for assessing the interrelationship between cardiac and cerebral circulations in elderly subjects: a preliminary study. Ultrasound Med Biol 18: 45–49.PubMedCrossRefGoogle Scholar
  9. 9.
    Schweizer J, Oehmichen F (1992) Erfahrungen bei der Anwendung der farbkodierten intrakraniellen Duplexsonographie. VASA 21: 299–302.PubMedGoogle Scholar
  10. 10.
    Sorteberg W, Langmoen TA, Lindgaard K-F, Nornes H (1990) Side-to-side differences and day-to-day variations of transcranial Doppler parameters in normal subjects. J Ultrasound Med 9: 403–409.PubMedGoogle Scholar
  11. 11.
    Yoshimura S, Furuhata H, Suzuki N, et al (1982) Non-invasive and quantitative measurement of volume flow-rate in internal and external carotid and vertebral arteries by ultrasound. J Jpn Coll Angiol 22: 191–198.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • G. du Boulay
    • 1
  • J. N. H. Brunt
    • 2
  • A. Wallis
    • 1
  1. 1.Institute of NeurologyNational Hospital, Queen ScareLondonEngland
  2. 2.Clatterbridge Centre for OncologyMerseysideEngland

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