Stereotactic gamma radiosurgery for malignant pineal tumours
Seven patients with pineal tumours, including three malignant teratomas, two malignant germ cell tumours, one germinoma and one pineoblastoma were treated by radiosurgery (RS). Their mean age was 13.7 years. RS has been applied to residual pineal tumours after surgical resection, conventional irradiation, and/or chemotherapy. Those multimodality treatments were also used after RS in some cases. In five of seven cases, the tumours were stable or decreased in size with a mean follow-up time of 18.9 months after RS. Dissemination in the cerebrospinal fluid space developed in four patients, two of whom died 12 and 13 months after RS, respectively.
Key wordsPineal body Germ cell tumour Pineoblastoma Radiosurgery Gamma knife
Unable to display preview. Download preview PDF.
- 2.Gzirjak S, Vajda J, Pasztor E (1992) Management of pineal region tumours. Neurol Res 14:241–247.Google Scholar
- 6.Kobayashi T, Yoshida J, Noda S, Kida Y, Teraoka M, Itoh J (1990) Combination chemotherapy with CDDP and etoposide (P-E therapy) for intracranial germ-cell tumors. Shouni No Noshinkei 15:409–416.Google Scholar
- 7.Nakagawa K, Aoki Y, Akanuma A, Sakata K, Karasawa K, Terahara A, Onogi Y, Hasezawa K, Muta N, Sasaki Y (1992) Radiation therapy of intracranial germ cell tumors with radio-sensitivity assessment. Radiat Oncol 10:55–61.Google Scholar