Acetazolamide-enhanced MR angiography of intracranial aneurysms
The purpose of our study was to evaluate the enhancing effect of acetazolamide in three-dimensional time-of-flight magnetic resonance angiography (MRA) for the diagnosis of intracranial aneurysms. MRA obtained at 1.5 T before and after acetazolamide administration was compared in a group of five patients without aneurysms and another group of seven patients with seven aneurysms. In each patient, distal arterial branches were more clearly demonstrated on MRA with the administration of acetazolamide than without. Four of the seven aneurysms (mean diameter, 9.0 mm) were better depicted after the acetazolamide infusion. In the remaining three aneurysms (mean diameter, 4.7 mm), no significant change was noted. This method improves the visualisation of distal small arteries and provides better images of relatively large aneurysms.
Key wordsMagnetic resonance angiography Intracranial aneurysm Acetazolamide Contrast media
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