Brain and spinal MRI in patients with systemic lupus erythematosus
We have examined 80 patients with systemic lupus erythematosus. Of 127 head MRI studies 75 showed parenchymal changes. Brain MRI findings were classified roughly into six groups: multiple high-intensity spots on T2-weighted images, 28 studies; infarction, 33 studies; transient high-intensity lesions on T2-weighted images, 8 studies; sinus thrombosis, 3 studies (1 patient); diffuse intracranial calcification, 2 studies; inflammation, 1 study. Significant differences were noted between MRI positive and MRI negative patients with regard to age and duration of the disease. Patients with MRI lesions were significantly older than MRI negative patients, and had a longer duration of the disease. There was no significant difference in the two groups with regard to lupus anticoagulant and the level of anticardiolipin antibody.
key wordsMagnetic resonance imaging Systemic lupus erythematosus
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