Idiopathic and Organic Presentations of Schizophrenia

  • M. R. Trimble
Conference paper


The term “idiopathic” has been used in medicine for many years as a shield to hide our ignorance regarding aetiology and pathogenesis of many diseases. It has been customary to draw distinctions between syndromes secondary to a known or assumed organic cause, and the idiopathic, synonyms for the latter being cryptogenic, essential, and endogenous. The presumption has been that causes in such cases are likely to have a substantial genetic basis.


Temporal Lobe Frontal Lobe Temporal Lobe Epilepsy Frontal Lobe Function Dopamine Hypothesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bleuler E (1950) Dementia praecox or the group of schizophrenias. International Universities Press, New YorkGoogle Scholar
  2. Bogerts B, Hantsch J, Herzer M (1983) A morphometric study of the dopamine containing cell groups in the mesencephalon of normals, Parkinson patients and schizophrenics. Biol Psychiatry 18:951Google Scholar
  3. Bruton CJ (1988) The neuropathology of temporal lobe epilepsy. Oxford University Press, Oxford (Maudsley monograph, no 31)Google Scholar
  4. Davison K, Bagley CR (1969) Schizophrenia-like psychoses associated with organic disorders of the central nervous system: a review of the literature. In: Herrington RN (ed) Current problems in neuropsychiatry. Headley Brothers, Ashford, Kent (British Journal of Psychiatry, special publication no 4)Google Scholar
  5. Denning TR, Berrios G (1989) Wilson’s disease. Psychiatric symptoms in 195 cases. Arch Gen Psychiatry 46:1126–1134CrossRefGoogle Scholar
  6. Feinstein A, duBoulay G, Ron M (1992) Psychotic illness in multiple sclerosis. Br J Psychiatry 161:680–685PubMedCrossRefGoogle Scholar
  7. Freud S (1964) An outline of psychoanalysis. In: The complete psychological works of Sigmund Freud, vol 23. Hogarth, London, pp 141–207Google Scholar
  8. International League against Epilepsy (1985) Proposal for classification of the epilepsies and epileptic syndromes. Epilepsia 26:268–278CrossRefGoogle Scholar
  9. Kraepelin E (1919) Dementia praecox and paraphrenia. Livingstone, EdinburghGoogle Scholar
  10. Perez MM, Trimble MR (1980) Epileptic psychosis - diagnostic comparison with process schizophrenia. Br J Psychiatry 137:245–249PubMedCrossRefGoogle Scholar
  11. Perez MM, Trimble MR, Murray MF, Reider I (1985) Epileptic psychosis: an evaluation of PSE profiles. Br J Psychiatry 146:155–163PubMedCrossRefGoogle Scholar
  12. Ring HA, Trimble MR, Costa DC, Moriarty J, Verhoeff NPLG, Ell PJ (1994) Striatal dopamine receptor binding in epileptic psychoses. Biol Psychiatr 35:375–380CrossRefGoogle Scholar
  13. Rogers D (1992) Motor disorder in psychiatry. Wiley, ChichesterGoogle Scholar
  14. Slater E, Beard AW (1963) The schizophrenia-like psychoses of epilepsy. Br J Psychiatry 109: 95–150PubMedCrossRefGoogle Scholar
  15. Stevens J (1986) Clinico-pathological correlations of schizophrenia. Arch Gen Psychiatry 43:115CrossRefGoogle Scholar
  16. Toone BK, Garralda ME, Ron MA (1982) The psychoses of epilepsy and the functional psychoses: a clinical and phenomenological comparison. Br J Psychiatry 141:256–261PubMedCrossRefGoogle Scholar
  17. Trimble MR (1981) Neuropsychiatry. Wiley, ChichesterGoogle Scholar
  18. Trimble MR (1988) Biological psychiatry. Wiley, ChichesterGoogle Scholar
  19. Trimble MR (1991) The psychoses of epilepsy. Raven, New YorkGoogle Scholar
  20. Trimble MR (1994) , 2nd edn. Wiley, ChichesterGoogle Scholar
  21. Trimble MR, Rogers D (1987) Neurological disorder in schizophrenia. In: Henn FA, Delisi LE (eds) Schizophrenia, vol 2. Elsevier Science, Amsterdam, pp 439–465Google Scholar
  22. Wong DF, Wagner HN, Tune LE et al (1986) Positron emission tomography reveals D2 receptors in drug naive schizophrenics. Science 234:1558–1563PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • M. R. Trimble
    • 1
  1. 1.Institute of NeurologyLondonUK

Personalised recommendations