Abstract
Many ideas proposed by clinicians working around the time of the first descriptions of schizophrenia are now being re-researched and honed by the tools of modern psychiatric research: neuroimaging, genetics and epidemiology. These four chapters are excellent examples.
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References
Asarnow RF, Asarnow JR, Strandburg R (1989) Schizophrenia: a developmental prospective. In: Tackle D, Cicchetti L (eds) The emergence of a discipline: Rochester symposium on development psychopathology, vol 1. Erlbaum, Hillsdale, New Jersey
Berman KF, ZEC RF, Weinberger DR (1986) Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. 2. Role of neuroleptic treatment, attention, and mental effort. Arch Gen Psychiatry 42:126–135
Birkett PBL, Griffiths TD, Frangou S, Sharma T, Sigmundson T, Murray RM, Reveley A (1994) Neuropsychology in familial schizophrenia. Schizophr Bull (in press)
Bruton CJ, Crow TJ, Frith CD, Jonstone EC, Owens DGC, Roberts GW (1990) Schizophrenia and the brain: a prospective clinico-neuropathological study. Psychol Med 20:285–304
Castle DJ, Murray RM (1991) The neurodevelopmental basis of sex differences in schizophrenia. Psychol Med 21:565–575
Castle DJ, Abel K, Takei N, Murray RM. The relationship between schizophrenia in women and affective disorder. Schizophr Bull (submitted)
Clouston TS (1892) Clinical lectures on mental diseases, 3rd edn. Churchill, London
Done DJ, Crow TJ, Johnstone EC, Sacker A (1993) Childhood antecedents of schizophrenia and affective illness: social adjustment at ages 7 & 11. Br Med J (in press)
Farmer A, McGuffin P, Gottesman II (1987) Twin concordance for DSM-III schizophrenia. Arch Gen Psychiatry 44:634–641
Frith CD, Friston KJ, Liddle PF, Frackowiak RSJ (1992) The left medial temporal region and schizophrenia; a PET study. Brain 115:367–382
Gottesman II, Sheilds J (1972) Schizophrenia and genetics: a twin study perspective. Academic, London
Green MF, Satz P, Soper HV et al (1987) Relationship between physical anomolies and age of onset of schizophrenia. Am J Psychiatry 144:666–669
Häfner H, Behrens S, deVry J, Gattaz WF (1991a) Oestradiol enhances the vulnerability threshold for schizophrenia in women by an early effect in dopaminergic neurotransmission. Eur Arch Psychiatry Clin Neurosci 241:65–68
Häfner H, Behrens S, de Vry J, Gattaz WF (1991b) An animal model for the effects of estradiol on dopamine-mediated behaviour - implications for sex differences in schizophrenia. Psychiatry Res 38:125–134
Jablensky A, Sartorius N, Ernberg G, Anker M, Korten A, Cooper JE, Day R, Bertelsen A (1992) Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization ten-country study. Psychol Med Monogr Suppl 20:40
Jones PB, Harvey I, Lewis SW, Toone BK, Van Os J, Williams M, Murray RM. Cerebral ventrical dimensions as risk factors of schizophrenia and effective psychosis. An epidemiological approach to analysis. Psychol Med (submitted)
Kleist K (1934a) Gehirnpathologie. Barth, Leipzig
Kleist K (1934b) Kriegverletzungen des Gehirn in ihre Bedeutung für Hirnlokalisation und Hirnpathologie. Barth, Leipzig
Lewis SW (1990) X-Ray CT in schizophrenia: fifteen years on. Br J Psychiatry 157(9): 16–24
Liddle PF (1984) Chronic schizophrenic symptoms, cognitive function and neurological impairment. Thesis, Royal College of Psychiatrists, London
Liddle PF (1987) The symptoms of chronic schizophrenia: a re-examination of the positive-negativce dichotomy. Thesis, Royal College of Psychiatrists. Br J Psychiatry 15:145–151
Marshall EJ, Revely AM, Coid B, Birkett PBL, Murray RM (1993) The Maudsley schizophrenic twin series. A 25 year follow-up: concordance and heritability for operationally defined schizophrenia. Arch Gen Psychiatry (submitted)
McGrath J, Murray RM (1994) Early risk factors for schizophrenia: from conception to birth. In: Weinberger D, Hirsch S (in press)
McGuire PK, Shah GMS, Murray RM (1993) Increased blood flow in Broca’s area during auditory hallucinations in schizophrenia. Lancet 342:703–706
Mednick S (1993) Presentation to NATO Advanced Study Insitute on fetal brain development and schizophrenia. 22 Sept 1 Oct. II Ciocco Hotel, Italy
Murray RM, Lewis SW, Reveley AM (1985) Towards an aetiological classification of schizophrenia. Lancet i: 1023–1026
Murray RM, Lewis SW, Owen M, Foerster A (1988) The neurodevelopmental origins of dementia praecox. In: Bebbington P, McGuffin P (eds) Schizophrenia: the major issues. Heinmann, London, pp 90–106
Murray RM, Jones PB, O’Callaghan E, Takei N, Sham P (1992a) Genes, viruses and neurodevelopmental schizophrenia. J Psychiatric Res 26:225–235
Murray RM, O’Callaghan E, Castle DJ, Lewis SW (1992b) A neurodevelopmental approach to the classification of schizophrenia. Schizopr Bull 18:319–332
Peralta V, deLeon J, Cuesta MJ (1992) Are there more than two syndromes in schizophrenia? A critique of the positive-negative dichotomy. Br J Psychiatry 161:335–343
Perez MM, Trimble MR, Murray MF, Reider I (1985) Epileptic Psychosis: An evaluation of PSE profiles. Br J Psychiatry 146:155–163
Ron M, Harvey I (1990) The brain in schizophrenia. J Neurol Neurosurg Psychiatry 53:725–726
Sham PC, Jones PB, Russel A, Foerster A, Gilvary, Bebbington P, Lewis SW, Toone BK, Murray RM (1993) Age at onset, sex and familial psychiatric morbidity in schizophrenia. Report from the Camberwell Collaborative Psychosis Study. Br J Psychiatry (submitted)
Slater E, Beard AW (1963) The schizophrenia-like psychoses of epilepsy. Br J Psychiatry 109:95–150
Takei N, O’Callaghan E, Sham P, Glover G, Murray RM (1994) Does pre-natal influenza divert susceptible females from later depressive psychosis to schizophrenia? Acta Psychiatr Scand (in press)
van Os J, Fahy T, Jones P, Harvey I, Lewis S, Toone B, Maurray RM et al (1994) Psychopatholo-gical syndromes in the functional psychoses and their prognostic significance, (submitted)
van Os J, Fahy T, Bebbington P, Jones P, Wilkins SW, Sham P, Russell A, Gilvary K, Lewis S, Toone B, Maurray RM (1994) The influence of life events on the subsequent course of psychotic illness. Psychol Med (in press)
Vita A et al (1992) Familial and sporadic schizophrenia: a meta-analysis. Presentation to the Association of European Psychiatrists, Barcelona, Nov 1992
Walsh C, Asherson T, Sham P, Castle D, Williams J, Taylor C, Clements A, Watt D, Sargeant M, Owen M, Gill M, McGuffin P, Murray RM (1994) Age of onset of schizophrenia in multiply affected families is early and shows no sex difference, (submitted)
Weinberger DR, Berman KF, Zee RF (1986) Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. 1. Regional cerebral blood flow evidence. Arch Gen Psychiatry 43: 114–124
Weinberger DR Berman KF Illowsky BP (1988) Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. 3. A new cohort and evidence for a monoaminergic mechanism. Arch Gen Psychiatry 45:609–615
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© 1995 Springer-Verlag Berlin Heidelberg
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Murray, R.M., Jones, P. (1995). Schizophrenia: Disease or Syndrome? Discussion. In: Häfner, H., Gattaz, W.F. (eds) Search for the Causes of Schizophrenia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79429-2_11
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DOI: https://doi.org/10.1007/978-3-642-79429-2_11
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