Abstract
Bacterial endotoxin (lipopolysaccharide, LPS) is the cell wall component of gram-negative bacteria responsible for initiation of fever, cardiovascular shock and severe disturbances in haemostatic-thrombotic balance-disseminated intravascular coagulation (DIC). Interactions between LPS and plasma, circulating blood cells and endothelium are of great interest since many deleterious effects of LPS during septicaemia are the result of the activation of a haemostatic-thrombotic system brought about by these interactions.
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Radomski, M.W. (1995). The Role of Nitric Oxide in Vascular Haemostasis and Thrombosis: Implications for Septicaemia and Cell Damage. In: Schlag, G., Redl, H. (eds) Shock, Sepsis, and Organ Failure — Nitric Oxide. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79343-1_9
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