Abstract
In 1984, work was begun on a 100-ml stroke volume roller-screw-type electric motor-driven total artificial heart at the Pennsylvania State University. The pumping system utilized two seam-free segmented polyurethane sacs housed within semi-rigid polysulfone cases. Size 25-mm outlet and 29-mm inlet Delrin disk Bjork-Shiley convexo-concave valves were used in both the left and right blood pumps. Screw-on quick connects for the atria and great vessels were employed to facilitate implantation of the device. The blood pumps were attached to either end of the energy converter. The energy converter used a brushless DC motor to drive a roller-screw mechanism. Attached to the ends of the screw portion of the roller-screw mechanism were two pusher plates, which alternately compressed the blood sacs. This roller-screw system employed an external electronic automatic control system in all experiments. The system has been described extensively elsewhere [1–5]. This 100-cc stroke volume rollerscrew total artificial heart was implanted in 12 calves; one calf survived for 388 days [6, 7]. After the initial postoperative period, this animal thrived; it was eventually killed due to inadequate cardiac output. The results of these initial experiments were extremely encouraging, and work was begun on a 70-cc stroke volume device that would be capable of being orthotopically placed in a human patient.
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References
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© 1995 Springer-Verlag Berlin Heidelberg
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Rosenberg, G., Snyder, A.J., Weiss, W.J., Sapirstein, J.S., Pierce, W.S. (1995). In Vivo Testing of a Clinical-size Totally Implantable Artificial Heart. In: Unger, F. (eds) Assisted Circulation 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79340-0_22
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DOI: https://doi.org/10.1007/978-3-642-79340-0_22
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