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Could Kinins Contribute to the Vasculoprotective Effect of Potassium Supplementation?

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Experimental Hypertension and Therapeutic Progress: Vasodilation and Beyond

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Abstract

Calcium antagonists have set a gold Standard for antihypertensive drugs by adding to the hypotensive effect an action to prevent, and eventually cause the regression, of vascular hypertensive and age–related damage. Since the early 1980s, they have provided a stimulus for the investigation of the possible mechanisms involved in vasculoprotection and have promoted their study in the laboratory animal. In humans they have led to the INTACT and MIDAS trials for calcium Channel blockers and to the PROTECT trial for angiotensin-converting enzyme (ACE) inhibitors.

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Author information

Authors and Affiliations

  1. Departamentos de Nefrología y Obstetricia/Ginecología, Centro de Investigaciones Médicas, Faeultad de Medicina, Pontificia Universidad Católica, Casilla 114-D, Santiago, Chile

    Gloria Valdés

  2. Departamento de Ciencias Fisiológicas, Facultad de Ciencias Biológicas, Pontificia Universidad Católica, Casilla 114-D, Santiago, Chile

    Carlos P. Vio

Authors
  1. Gloria Valdés
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  2. Carlos P. Vio
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Editor information

Editors and Affiliations

  1. Cardiovascular and Arteriosclerosis Research, Bayer AG, Aprather Weg 18a, 42096, Wuppertal, Germany

    Bernward Garthoff DVM  & Andreas M. Knorr Ph.D.  & 

  2. International Research Pharma, Bayer AG, Aprather Weg 18a, 42096, Wuppertal, Germany

    Wolf-Dieter Busse Ph.D. (Professor) (Professor)

  3. Coordination International Research, Bayer AG, Aprather Weg 18a, 42096, Wuppertal, Germany

    Friedel Seuter Ph.D.

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© 1995 Springer-Verlag Berlin Heidelberg

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Valdés, G., Vio, C.P. (1995). Could Kinins Contribute to the Vasculoprotective Effect of Potassium Supplementation?. In: Garthoff, B., Knorr, A.M., Busse, WD., Seuter, F. (eds) Experimental Hypertension and Therapeutic Progress: Vasodilation and Beyond. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79338-7_8

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  • DOI: https://doi.org/10.1007/978-3-642-79338-7_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-58545-9

  • Online ISBN: 978-3-642-79338-7

  • eBook Packages: Springer Book Archive

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