Abstract
Molecular dynamics simulations can shed light on subnanosecond phenomena in nucleic acids interacting with proteins. Results from studies of Ribonuclease T1, the glucocortoid receptor DNA binding domain, and short model nucleotides are reported, and compared to experimental NMR and fluorescence data. Events occurring on different timescales will be discussed, together with an analysis of the the role of water, especially in the interface between protein and DNA.
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Nilsson, L. (1995). Dynamics of Nucleic Acids and Nucleic Acid:Protein Complexes. In: Mosekilde, E., Mouritsen, O.G. (eds) Modelling the Dynamics of Biological Systems. Springer Series in Synergetics, vol 65. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79290-8_8
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DOI: https://doi.org/10.1007/978-3-642-79290-8_8
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