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Reproductive Potential After Adjuvant Chemotherapy for Breast Cancer

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Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 140))

Abstract

The 10-year update of the world-wide overview of breast cancer treatment (Early Breast Cancer Trialists’ Collaborative Group 1992) has confirmed that adjuvant systemic therapy can alter the course of breast cancer. In women younger than 50 years of age (i.e. in premenopausal women), highly significant reductions in the annual rates of both recurrence (37%) and death (27%) are produced by adjuvant combination chemotherapy when compared with local-regional treatment alone.

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References

  • Bonadonna G (1992) Evolving concepts in the systemic adjuvant treatment of breast cancer. Cancer Res 52: 2127–2137

    PubMed  CAS  Google Scholar 

  • Boring CC, Squires TS, Tong T (1993) Cancer statistics, 1993. CA 43: 7–26

    PubMed  CAS  Google Scholar 

  • Danforth DN (1991) How subsequent pregnancy affects outcome in women with a prior breast cancer. Oncology 5: 23–32

    PubMed  Google Scholar 

  • Donegan WL (1977) Pregnancy and breast cancer. Obstet Gynecol 50: 244–251

    PubMed  CAS  Google Scholar 

  • Dow KH, Harris JR, Roy C (1994) Pregnancy after breast-conserving surgery and radiation therapy for breast cancer. Monogr Natl Cancer Inst 16: 131–137

    PubMed  Google Scholar 

  • Early Breast Cancer Trialists' Collaborative Group (1992) Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31000 recurrences and 24 000 deaths among 75 000 women. Lancet 339:1–15, 71–85

    Google Scholar 

  • Mulvihill JJ, McKeen EA, Rosner F, Zarrabi MH (1987) Pregnancy outcome in cancer patients. Experience in a large cooperative group. Cancer 60: 1143–1150

    Google Scholar 

  • Myers SE, Schilsky RL (1992) Prospects for fertility after cancer chemotherapy. Semin Oncol 19: 597–604

    PubMed  CAS  Google Scholar 

  • Reichman BS, Green KB (1994) Breast cancer in young women: effect of chemotherapy on ovarian function, fertility, and birth defects. Monogr Natl Cancer Inst 16: 125–129

    PubMed  Google Scholar 

  • Sutton R, Buzdar AU, Hortobagyi GN (1990) Pregnancy and offspring after adjuvant chemotherapy in breast cancer patients. Cancer 65: 847–850

    Article  PubMed  CAS  Google Scholar 

  • Valagussa P, Moliterni A, Zambetti M, Bonadonna G (1993) Long-term sequelae from adjuvant chemotherapy. Recent Res Cancer Res 127: 247–255

    Article  CAS  Google Scholar 

  • Ventura SJ (1989) First births to older mothers 1970–1986. Am J Public Health 79: 1675–1684

    Article  PubMed  CAS  Google Scholar 

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© 1996 Springer-Verlag Berlin Heidelberg

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Valagussa, P., De Candis, D., Antonelli, G., Bonadonna, G. (1996). Reproductive Potential After Adjuvant Chemotherapy for Breast Cancer. In: Senn, H.J., Gelber, R.D., Goldhirsch, A., Thürlimann, B. (eds) Adjuvant Therapy of Breast Cancer V. Recent Results in Cancer Research, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79278-6_31

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  • DOI: https://doi.org/10.1007/978-3-642-79278-6_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79280-9

  • Online ISBN: 978-3-642-79278-6

  • eBook Packages: Springer Book Archive

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