Potential Role of CD28-B7 Interactions in the Growth of Myeloma Plasma Cells
Multiple myeloma is a malignancy of plasma cells. Patients with myeloma have associated immune deficiencies, including decreased numbers of B cells in the peripheral blood and corresponding decreased humoral responses. Myeloma patients also show significant alterations in T cell function. There are decreased numbers of CD4+ T cells while CD8+ T cells are normal to slightly increased [1,2].
KeywordsLymphoma Tyrosine Polypeptide Myeloma Thymidine
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