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Clinical Trials for the Treatment of Sepsis pp 141–156Cite as

What Determines Prognosis in Sepsis?

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Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 19))

Abstract

Patients presenting with sepsis are complexly ill with multiple risk factors for short-term mortality. In order to fully represent this complexity, an accurate comprehensive individual patient risk mortality based on reliable risk factors available at the time of treatment can be constructed from large, contemporary, clinically-accurate databases. The individual patient risk assessments produced by this approach can be used within clinical evaluations to insure that baseline risks for mortality were equally distributed among treatment groups and to investigate whether there is a relationship between baseline risk and efficacy of new therapeutic compounds.

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Authors
  1. W. A. Knaus
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  2. D. P. Wagner
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  3. F. E. Harrell
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Editor information

Editors and Affiliations

  1. Department of Critical Care, Victoria Hospital, 375 South Street, N6A 4G5, London, Ontario, Canada

    W. J. Sibbald

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© 1995 Springer-Verlag Berlin Heidelberg

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Knaus, W.A., Wagner, D.P., Harrell, F.E. (1995). What Determines Prognosis in Sepsis?. In: Vincent, JL., Sibbald, W.J. (eds) Clinical Trials for the Treatment of Sepsis. Update in Intensive Care and Emergency Medicine, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79224-3_9

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  • DOI: https://doi.org/10.1007/978-3-642-79224-3_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79226-7

  • Online ISBN: 978-3-642-79224-3

  • eBook Packages: Springer Book Archive

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