Skip to main content
SpringerLink
Log in
Book cover

Clinical Trials for the Treatment of Sepsis pp 370–385Cite as

Economic Evaluation in the Critical Care Literature

  • Chapter

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 19))

Abstract

Two interwoven themes have emerged over the last decade which illustrate the compelling need for more rigorous economic evaluation in the future of critical care research. First, the current tension over spiralling health care costs has reached its pinnacle in discussions about scarce resource allocation to the intensive care unit (ICU). In this setting, critically ill patients consume a large proportion of hospital budgets, usually in the last few days of life [1]. Thus, the highly skilled personnel, and complex, expensive technology utilized in the ICU make it particularly vulnerable to increasing health care costs [2].

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Detsky AS, Strieker SC, Mulley AG, Thibault GE (1981) Prognosis, survival and the expenditure of hospital resources for patients in an intensive care unit. N Engl J Med 305: 667–672

    Article  PubMed  CAS  Google Scholar 

  2. Jacobs P, Noseworthy TW (1990) National estimates of intensive care utilization and costs: Canada and United States. Crit Care Med 18: 1282–1286

    Article  PubMed  CAS  Google Scholar 

  3. Fuchs VH (1979) Who shall live? Basic Books, New York, New York, p 60

    Google Scholar 

  4. Cook DJ, Brun-Buisson C, Guyatt GH, Sibbald WJ (1994) Evaluation of new technology: The bronchoalveolar lavage for diagnosing ventilator-associated pneumonia. Crit Care Med (in press)

    Google Scholar 

  5. Weinstein MC, Stason WB (1977) Foundations of cost-effectiveness analysis for health and medical practices. N Engl J Med 296: 716–721

    Article  PubMed  CAS  Google Scholar 

  6. Warner KE, Hutton RC (1980) Cost-benefit and cost-effectiveness analysis in health care: Growth and composition of the literature. Med Care 11: 1069–1084

    Article  Google Scholar 

  7. Gill RS, Inman KJ, Eberhard JA, Sibbald WJ (1993) An evaluation of the health eco-nomic literature in the intensive care setting. Chest 104: 98S (Abst)

    Google Scholar 

  8. Campbell ML, Field BE (1991) Management of the patient with do not resuscitate status. Heart Lung 20: 345–348

    PubMed  CAS  Google Scholar 

  9. Drummond MF, Stoddart GL, Torrance GW (1986) Basic types of economic evaluation. In: Drummond MF, Stoddart GL, Torrance GW (eds) Methods for the economic evaluation of health care programs. Oxford Medical Publications, Oxford, pp 5–17

    Google Scholar 

  10. Neuhauser D, Lewicki AM (1975) What do we gain from the sixth stool guaiac? N Engl J Med 293: 226–228

    Article  PubMed  CAS  Google Scholar 

  11. Department of Clinical Epidemiology & Biostatistics (1981) How to read clinical journals: To understand an economic evaluation. Can Med Assoc J 130: 1428–1433

    Google Scholar 

  12. Department of Clinical Epidemiology & Biostatistics (1981) How to read clinical journals: To distinguish useful from useless or even harmful therapy. Can Med Assoc J 124: 1156–1162

    Google Scholar 

  13. Mohsenifar Z, Hay A, Hay J, Lewis MI, Koerner SK (1993) Gastric intramural pH as a predictor of success or failure in weaning patients from mechanical ventilation. Ann Intern Med 119: 794–798

    PubMed  CAS  Google Scholar 

  14. Lowson KV, Drummond MF, Bishop JM (1981) Costing new services: Long-term domiciliary oxygen therapy. Lancet 2: 1146–1149

    Article  Google Scholar 

  15. Reynell PC, Reynell MC (1972) The cost-benefit analysis of a coronary care unit. Br Heart J 34: 897–900

    Article  PubMed  CAS  Google Scholar 

  16. Doubilet P, Weinstein MC, McNeil BJ (1986) Use and misuse of the term “cost-effective” in medicine. N Engl J Med 314: 253–256

    Article  PubMed  CAS  Google Scholar 

  17. Kelly RJ, Cowan RJ, Feree CB, Raban M, Maynard CD (1979) Efficacy of radionuclide scanning in patients with lung cancer. JAMA 242: 2855–2857

    Article  PubMed  CAS  Google Scholar 

  18. Krumholz HM, Pasternak RC, Weinstein MC, et al (1992) Cost-effectiveness of thrombolytic therapy with streptokinase in elderly patients with suspected acute myocardial infarction. N Engl J Med 327: 7–13

    Article  PubMed  CAS  Google Scholar 

  19. Schulman KA, Glick HA, Rubin H, Eisenberg JM (1991) Cost-effectiveness of HA-1A therapy for gram-negative sepsis. JAMA 266: 3466–3471

    Article  PubMed  CAS  Google Scholar 

  20. Chalfin DB, Holbein MEB, Fein AM, Carlon C (1993) Cost-effectiveness of monoclonal antibodies to gram-negative endotoxin in the treatment of gram-negative sepsis in ICU patients. JAMA 269: 249–254

    Article  PubMed  CAS  Google Scholar 

  21. Weisbrod BA, Test MA, Stein LI (1980) Alternatives to mental hospital treatment: Economic cost-benefit analysis. Arch Gen Psych 37: 400–405

    CAS  Google Scholar 

  22. Boyle MH, Torrance GW, Sinclair JC, Horwood SP (1983) Economic evaluation of neonatal intensive care of very low birth weight infants. N Engl J Med 308: 1330–1337

    Article  PubMed  CAS  Google Scholar 

  23. Sackett DL (1981) How to read clinical journals: Why to read them and how to start reading them critically. Can Med Assoc J 124: 555–558

    Google Scholar 

  24. Tugwell PX (1981) How to read clinical journals: To learn the clinical course and prognosis of disease. Can Med Assoc J 124: 869–872

    Google Scholar 

  25. Haynes RB (1981) How to read clinical journals: To learn about a diagnostic test. Can Med Assoc J 124: 703–710

    Google Scholar 

  26. Guyatt GH, Sackett DL, Cook DJ and the Evidence-Based Medicine Working Group (1993) Users’ guides to the medical literature: Part I: How to use an article about therapy. JAMA 270: 2093–2095

    Article  PubMed  Google Scholar 

  27. Guyatt GH, Sackett DL, Cook DJ and the Evidence-Based Medicine Working Group (1993) Users’ guides to the medical literature: Part II: How to use an article about therapy or prevention. JAMA 270: 2598–2601

    Article  PubMed  CAS  Google Scholar 

  28. Oxman AD, Cook DJ, Guyatt GH and the Evidence-Based Medicine Working Group (1994) Users’ guides to the medical literature: How to use an overview. JAMA (in press)

    Google Scholar 

  29. Cook DJ, Jaeschke R, Guyatt GH (1992) Critical appraisal of therapeutic interventions in the intensive care unit: Human monoclonal antibody treatment in sepsis. J Intensive Care Med 7: 275–282

    PubMed  CAS  Google Scholar 

  30. Fuchs VR (1980) What is CBA/CEA and why are they doing this to us? N Engl J Med 303: 937–938

    Article  PubMed  CAS  Google Scholar 

  31. Inman KJ, Sibbald WJ, Rutledge FS, Clark BJ (1993) Clinical utility and cost-effective- ness of an air suspension bed in the prevention of pressure ulcers. JAMA 269: 1139–1143

    Article  PubMed  CAS  Google Scholar 

  32. Luce BR, Elixhauser A (1990) Estimating costs in the economic evaluation of health services. Int J Tech Assess Health Care 6: 57–75

    Article  CAS  Google Scholar 

  33. Torrance GW, Feeny DH (1989) Utilities and quality-adjusted life years. Int J Tech Assess Health Care 5: 559–575

    Article  CAS  Google Scholar 

  34. Guyatt GH, Feeny DH, Patrick DL (1993) Measuring health-related quality of life. Ann Intern Med 118: 622–629

    PubMed  CAS  Google Scholar 

  35. Naylor D, Lington AL (1986) Allocation of health care resources: A challenge for the medical profession. Can Med Assoc J 134: 333–340

    CAS  Google Scholar 

  36. Stoddart GL, Barer ML (1992) Toward integrated medical resource policies for Canada: Analytic framework for policy development. Can Med Assoc J 146: 1169–117

    CAS  Google Scholar 

  37. Stoddart GL, Barer ML (1992) Toward integrated medical resource policies for Canada: Improving effectiveness and efficiency. Can Med Assoc J 147: 1653–1660

    CAS  Google Scholar 

Download references

Authors
  1. D. J. Cook
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Critical Care, Victoria Hospital, 375 South Street, N6A 4G5, London, Ontario, Canada

    W. J. Sibbald

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Cook, D.J. (1995). Economic Evaluation in the Critical Care Literature. In: Vincent, JL., Sibbald, W.J. (eds) Clinical Trials for the Treatment of Sepsis. Update in Intensive Care and Emergency Medicine, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79224-3_24

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-79224-3_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79226-7

  • Online ISBN: 978-3-642-79224-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation