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Messung der Gehirndurchblutung mit 99mTc-d,I-HMPAO

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Single-Photon-Emissions-Computertomographie (SPECT) des Gehirns

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Zusammenfassung

Zur tomographischen Aufnahme der Gehirndurchblutung müssen ca. 200 000 Counts (Cts) pro Schicht aufintegriert werden, um einen guten Kompromiß zwischen Auflösungsvermögen und Rauschen zu erhalten. Bei einer tolerierbaren Applikation von 500-800 MBq 99mTc und einem Uptake von einigen Prozent in das Gehirn beträgt die Aufnahmedauer ca. 30 min. Voraussetzung der transaxialen Tomographie ist jedoch, daß während der gesamten Aufnahmedauer das Muster der Aktivitätsanreicherung konstant bleibt. Eine Pharmakokinetik, die das Muster der Gehirndurchblutung für nur wenige Sekunden oder Minuten aufrechterhält, ist daher für hochauflösende Tomogramme nicht geeignet.

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Authors
  1. K. Reichmann
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  1. Abt. Nuklearmedizin, Bundeswehrzentralkrankenhaus Koblenz, Rübenacherstr. 170, 56072, Koblenz, Germany

    H. J. Wieler (Leitender Arzt) (Leitender Arzt)

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Reichmann, K. (1995). Messung der Gehirndurchblutung mit 99mTc-d,I-HMPAO. In: Wieler, H.J. (eds) Single-Photon-Emissions-Computertomographie (SPECT) des Gehirns. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79222-9_4

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  • DOI: https://doi.org/10.1007/978-3-642-79222-9_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79223-6

  • Online ISBN: 978-3-642-79222-9

  • eBook Packages: Springer Book Archive

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