Gemcitabine Therapy in Non-Small Cell Lung Cancer: A Review

  • Thierry Le Chevalier
Conference paper
Part of the ESO Monographs book series (ESO MONOGRAPHS)

Abstract

The treatment of advanced non-small cell lung cancer (NSCLC) has not made very significant progress with regard to response rates and survival in the last decade. Few single agents have, in large studies, achieved response rates of more than 15%, while combination treatment gives response rates of 25% to 35% [1–4]. Several randomised studies comparing chemotherapy with best supportive care have yielded predominantly slightly favourable results for chemotherapy [5]. Two recent meta-analyses of the literature indicated a significant but modest survival advantage for the use of platinum-containing combination treatment compared with best supportive care [6,7].

Keywords

Toxicity Platinum Oncol Neutropenia Thrombocytopenia 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • Thierry Le Chevalier
    • 1
  1. 1.Comité de Pathologie ThoraciqueInstitut Gustave RoussyVillejuif CedexFrance

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