Abstract
Many heresies of the past have become the orthodox views of later times. In fact, progress in science is made possible through the generation of new and different ideas that are then tested for validity. It is common and natural for these new ideas to be met with resistance. The tension between the established and the new serves at least as an incentive to determine which is the better concept. In some cases, useful understandings emerge from the dialog that results from the opposing ideas. It is also possible, of course, for the new ideas to be wrong. In this case the shortcomings of the proposed new perspective usually become obvious over time, and the pursuit of the new concept becomes merely a temporary diversion.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bookman DE (1988) Early association of duodenal contents and blood with acini during experimental pancreatitis. Int J Pancreatol 3:333–342
Bockman DE, Schiller WR, Anderson MC (1971) Route of retrograde flow in the exocrine pancreas during ductal hypertension. Arch Surg 103:321–329
Bockman DE, Schiller WR, Suriyapa C, Mutchler JHW, Anderson MC (1973) Fine structure of early experimental acute pancreatitis in dogs. Lab Invest 28:548 – 592
Bockman DE, Black 0 Jr, Mills LR, Webster PD (1978) Origin of tubular complexes developingduring induction of pancreatic adenocarcinoma by 7,12-dimethylbenz(a)anthracene. Am J Pathol 90:645–658
Bockman DE, Boydston WR, Anderson MC (1982) Origin of tubular complexes in human chronic pancreatitis. Am J Surgery 144:243–249
Bockman DE, Büchler M, Beger HG (1986) Ultrastructure of human acute pancreatitis. Int J Pancreatol 1:141 –153
Elsasser HP, Adler G, Kern HF (1986) Time course and cellular source of pancreatic regeneration after acute necrohemorrhagic pancreatitis. Pancreas 1:421–429
Flaks B, Moore MA, Flaks A (1981) Ultrastructural analysis of pancreatic carcinogenesis. IV. Pseudoductular transformation of acini in the hamster pancreas during N-nitroso-bis-(2-hydroxypropyl)amine carcinogenesis. Carcinogenesis 2:1241–1253
Foulis AK (1980) Histological evidence of initiating factors in acute pancreatitis in man. J Clin Pathol 33:1125 –1131
Foulis AK (1993) Morphology of acute pancreatitis. In: Beger HG, Büchler M, Malfertheiner P (eds) Standards in pancreatic surgery. Springer, Berlin Heidelberg New York, pp 44–52
Giorgi D, Bernard JP, Lapointe R, Dagorn J-C (1984) Regulation of amylase messenger RNA concentrations in rat pancreas by food content. EMBO J 3:1521–1524
Iovanna JL, Keim V, Michel R, Dagorn J-C (1991) Pancreatic gene expression is altered during acute experimental pancreatitis in the rat. Am J Physiol 261:485 – 489
Iovanna JL, Lechene de la Porte P, Dagorn J-C (1992) Expression of genes associated with dedifferentiation and cell proliferation during pancreatic regeneration following acute pancreatitis. Pancreas 7:712– 718
Klar E, Endrich B, Messmer K (1990) Microcirculation of the pancreas: a quantitative study of physiology and changes in pancreatitis. Int J Microcirc Clin Exp 9:85 –101
Klöppel G, von Gerkan R, Dreyer T (1984) Pathomorphology of acute pancreatitis. Analysis of 367 autopsy cases and 3 surgical specimens. In: Gyr KE, Singer MV, Sarles H (eds) Pancreatitis — concepts and classification. Excerpta Medica, Amsterdam, pp 29–35
Lampel M, Kern HF (1977) Acute interstitial pancreatitis in the rat induced by excessive doses of pancreatic secretagogue. Virchows Arch [A] 373:97–117
Lechene de la Porte P, Iovanna JL, Odaira C, Choux R, Sarles H, Berger Z (1991) Involvement of tubular complexes in pancreatic regeneration following acute pancreatitis in the rat. Pancreas 6:298–306
Lombardi B, Estes LW, Longnecker DS (1975) Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet. Am J Pathol 79:465 – 475
Popper HL, Necheles H, Russell KC (1948) Transition of pancreatic edema into pancreatic necrosis. Surg Gynecol Obstet 87:79–82
Pour, P(1981) Experimental pancreatic ductal (ductular) tumors. In: Fitzgerald PJ, Morrison AB (eds) The pancreas. Williams and Wilkins, Balitmore, pp 113–139
Rao MS, Reddy JK (1980) Histogenesis of pseudo-ductular changes induced in the pancreas of guinea pigs treated with N-methyl-N-nitrosourea. Carcinogenesis 1:1027–1037
Schmidt H, Lankisch PG (1978) Fat necrosis — a cause of pancreatic parenchymal necrosis? Digestion 17:84–91
Schmitz-Moorman P (1981) Comparative radiological and morphological study of the human pancreas. IV. Acute necrotizing pancreatitis in man. Pathol Res Pract 171:325–335
Schmitz-Moorman P, von Wedel R, Agricola B, Himmelmann GW (1978) Studies of lipase-induced fat necrosis in rats. Pathol Res Pract 163:93–108
Storck G (1971) Fat necrosis in acute pancreatitis. Acta Chir Scand [Suppl] 417:1–36
Storck G (1972) Experimental fat necrosis in the rat. I. Studies with the vital microscope. Acta Chir Scand 138:69 – 77
Storck G, Hansson CG (1972) Experimental fat necrosis in the rat. II. A histopathological study. Acta Chir Scand 138:165 –169
Walker NI, Winterford CM, Kerr JFR (1992) Ultrastructure of the rat pancreas after experimental duct ligation. II. Duct and stromal cell proliferation, differentiation, and deletion. Pancreas 7:420 – 434
Wilson C, Imrie CW (1991) Experimental models of acute pancreatitis. In: Johnson CD, Imrie CW (eds) Pancreatitic disease. Springer, Berlin Heidelberg New York, pp 227–239
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Bockman, D.E. (1994). Pathomorphology of Acute Pancreatitis. In: Pederzoli, P., Cavallini, G., Bassi, C., Falconi, M. (eds) Facing the Pancreatic Dilemma. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79167-3_46
Download citation
DOI: https://doi.org/10.1007/978-3-642-79167-3_46
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-58284-7
Online ISBN: 978-3-642-79167-3
eBook Packages: Springer Book Archive