Opinion from Italy

  • G. Cavallini
  • V. Di Francesco
  • P. Bovo
  • B. Vaona
  • M. Filippini
  • L. Frulloni
  • M. Marcori
  • L. Rigo
  • M. P. Brunori
  • M. C. Andreaus
Conference paper


The Marseille-Rome classification appears to establish definitively the distinctive features of the various forms of chronic pancreatitis (CP). Essentially, the forms of CP with a lithogenic potential (chronic calcifying pancreatitis or pancreatic lithiasis) (CCP) are distinguished from other forms of the disease such as inflammatory CP, pancreatic fibrosis and chronic obstructive pancreatitis (COP) with different inflammatory components, all considered as being devoid of lithiasic characteristics [1]. The lithogenesis in the former chronic pancreatitis group is thought to be related mainly to pathogenetic mechanisms which are absent in the other forms of the disease, such as defective production and/or secretion of lithostatin (LS; a lectin-like protein which stabilizes the calcium present in pancreatic juice) or factors capable of influencing lithostatin secretion [2].


Chronic Pancreatitis Pancreatic Duct Primary Sclerosing Cholangitis Pancreatic Juice Main Pancreatic Duct 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • G. Cavallini
  • V. Di Francesco
  • P. Bovo
  • B. Vaona
  • M. Filippini
  • L. Frulloni
  • M. Marcori
  • L. Rigo
  • M. P. Brunori
  • M. C. Andreaus

There are no affiliations available

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