Skip to main content

Topische Antibiotikatherapie: Was wirkt? Gefährliche Resistenzentwicklung?

  • Conference paper
Fortschritte der praktischen Dermatologie und Venerologie

Part of the book series: Fortschritte der praktischen Dermatologie und Venerologie ((DERMATOLOGIE,volume 14))

  • 69 Accesses

Zusammenfassung

Die Ätiologie der Acne vulgaris ist multifaktoriell (Abb.1). Der Einsatz eines Antibiotikums bei der Acne vulgaris, unabhängig davon, ob topisch oder systemisch, setzt sich mit einem ganz bestimmten Teilfaktor auseinander, nämlich der mikrobiellen Besiedelung der Talgdrüsenfollikel.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Akamatsu H, Niwa Y, Kurokawa I et al (1991) Effects of subminimal inhibitory concentrations of minocycline on neutrophil chemotactic factor production in comedonal bacteria, neutrophil phagocytosis and oxygen metabolism. Arch Dermatol Res 283:524–528.

    Article  CAS  PubMed  Google Scholar 

  2. Akamatsu H, Kurokawa I, Nishijima S, Asada Y (1992) Inhibition of neutrophilic chemotactic factor produc tion in comedonal bacteria by subminimal inhibitory concentrations of erythromycin. Dermatologica 185:41–43.

    Article  CAS  Google Scholar 

  3. Bojar RA, Eady EA, Jones CE, Cuncliffe WJ, Holland KT (1994) Inhibition of erythromycin-resistant propionibacteria on the skin of acne patients by topi cal erythromycin with and without zinc. Br J Derma tol 130:329–336.

    Article  CAS  Google Scholar 

  4. Chalker DK, Shalita A, Smith JG, Swann RW (1983) A double-blind study of the effectiveness of a 3% eryth romycin and a 5% benzoyl peroxide combination in the treatment of acne vulgaris. J Am Acad Dermatol 9:933–936.

    Article  CAS  PubMed  Google Scholar 

  5. Eady EA, Cove JH, Holland KT, Cuncliffe WJ (1989) Erythromycin resistant propionibacteria in antibiotic treated acne patients: association with therapeutic fai lure. Br J Dermatol 121:51–57.

    Article  CAS  PubMed  Google Scholar 

  6. Eady EA, Jones CE, Tipper JL et al (1993) Antibiotic re sistant propionibacteria in acne: need for policies to modify antibiotic usage. Br Med J 306:555–556.

    Article  CAS  Google Scholar 

  7. Esterly NB, Furey NL, Flanagan LG (1978) The effect of antimicrobial agents on leukocyte chemotaxis. J Invest Dermatol 70:51–55.

    Article  CAS  PubMed  Google Scholar 

  8. Forssman T (1993) Antimikrobielle Akne-Therapie. Antibiotika-Resistenzen beachten. TW Dermatol 23:414–419.

    Google Scholar 

  9. Guin JD, Lummis WL (1982) Comedonal levels of free clindamycin following topical treatment with a 1% so lution of clindamycin phosphate. J Am Acad Derma tol 7:265–268.

    Article  CAS  Google Scholar 

  10. Harkaway KS, McGinley KJ, Foglia AN et al (1992) An tibiotic resistance patterns in coagulase-negative staphylococci after treatment with topical erythromycin, benzoyl peroxide, and combination therapy. Br J Der matol 126:586–590.

    CAS  Google Scholar 

  11. Leyden JJ (1976) Antibiotic resistant acne. Cutis 17:593–596.

    CAS  PubMed  Google Scholar 

  12. Naidoo J, Noble WC (1987) Skin as a source of transfe rable antibiotic resistance in coagulase-negative staphylococci. Zbl Bakt Suppl 16:225–234.

    Google Scholar 

  13. Noble WC (1990) Topical and systemic antibiotics: is there a rationale? Sem Dermatol 9:250–254.

    CAS  Google Scholar 

  14. Tucker SB, Tausend R, Cochran R, Flannigan SA (1984) Comparison of topical clindamycin phosphate, benzoyl peroxide, and a combination of the two for the treatment of acne vulgaris. Br J Dermatol 110:487–492.

    Article  CAS  PubMed  Google Scholar 

  15. Webster GF, Leyden JJ (1980) Production of serum-in dependent polymorphonuclear leukocyte chemotactic factors by Propionibacterium acnes. Inflammation 4:261–269.

    Article  CAS  PubMed  Google Scholar 

  16. Webster GF, Leyden JJ (1982) Mechanisms of Propioni bacterium acnes mediated inflammation in acne vul garis. Semin Dermatol 1:299–304.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Abeck, D. (1995). Topische Antibiotikatherapie: Was wirkt? Gefährliche Resistenzentwicklung?. In: Plewig, G., Korting, H.C. (eds) Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79156-7_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-79156-7_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79157-4

  • Online ISBN: 978-3-642-79156-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics